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bis[6-(5,6-dihydrochelerythrinyl)]amine

CAS# 165393-48-6

bis[6-(5,6-dihydrochelerythrinyl)]amine

2D Structure

Catalog No. BCN8232----Order now to get a substantial discount!

Product Name & Size Price Stock
bis[6-(5,6-dihydrochelerythrinyl)]amine: 5mg $638 In Stock
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bis[6-(5,6-dihydrochelerythrinyl)]amine: 200mg Please Inquire Please Inquire
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Quality Control of bis[6-(5,6-dihydrochelerythrinyl)]amine

Quality Control & MSDS

3D structure

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bis[6-(5,6-dihydrochelerythrinyl)]amine

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Chemical Properties of bis[6-(5,6-dihydrochelerythrinyl)]amine

Cas No. 165393-48-6 SDF Download SDF
PubChem ID 23279753 Appearance Powder
Formula C42H37N3O8 M.Wt 711.76
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name N-(1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridin-13-yl)-1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridin-13-amine
SMILES CN1C(C2=C(C=CC(=C2OC)OC)C3=C1C4=CC5=C(C=C4C=C3)OCO5)NC6C7=C(C=CC(=C7OC)OC)C8=C(N6C)C9=CC1=C(C=C9C=C8)OCO1
Standard InChIKey OZEFMOJRNJPFRQ-UHFFFAOYSA-N
Standard InChI InChI=1S/C42H37N3O8/c1-44-37-25(9-7-21-15-31-33(17-27(21)37)52-19-50-31)23-11-13-29(46-3)39(48-5)35(23)41(44)43-42-36-24(12-14-30(47-4)40(36)49-6)26-10-8-22-16-32-34(53-20-51-32)18-28(22)38(26)45(42)2/h7-18,41-43H,19-20H2,1-6H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of bis[6-(5,6-dihydrochelerythrinyl)]amine

The herbs of Macleaya cordata

Biological Activity of bis[6-(5,6-dihydrochelerythrinyl)]amine

Description1. BIS-[6-(5,6-dihydro-chelerythrinyl)] ether shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA).
TargetsAntifection

bis[6-(5,6-dihydrochelerythrinyl)]amine Dilution Calculator

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bis[6-(5,6-dihydrochelerythrinyl)]amine Molarity Calculator

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Preparing Stock Solutions of bis[6-(5,6-dihydrochelerythrinyl)]amine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.405 mL 7.0248 mL 14.0497 mL 28.0994 mL 35.1242 mL
5 mM 0.281 mL 1.405 mL 2.8099 mL 5.6199 mL 7.0248 mL
10 mM 0.1405 mL 0.7025 mL 1.405 mL 2.8099 mL 3.5124 mL
50 mM 0.0281 mL 0.1405 mL 0.281 mL 0.562 mL 0.7025 mL
100 mM 0.014 mL 0.0702 mL 0.1405 mL 0.281 mL 0.3512 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on bis[6-(5,6-dihydrochelerythrinyl)]amine

Chemical constituents, antimicrobial and antimalarial activities of Zanthoxylum monophyllum.[Pubmed:21341176]

Planta Med. 2011 Sep;77(13):1542-4.

From the leaves and bark of Zanthoxylum monophyllum, a new lignan, 3-methoxy-3',4'-methylenedioxylignan-4,8,9,9'-tetraol (1), has been isolated along with 22 known compounds (2- 23), fifteen of them reported for the first time from Z. monophyllum. Their chemical structures were elucidated using detailed spectroscopic studies and chemical analysis. All compounds were evaluated for antimicrobial and antiprotozoal activities. Alkaloids BIS-[6-(5,6-dihydro-chelerythrinyl)] ether (2) and 6-ethoxy-chelerythrine (4) exhibited strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA). Compound 4-methoxy-N-methyl-2-quinolone (9) exhibited significant activity against MRSA (IC50 value of 8.0 microM) while compound 5,8,4'-trihydroxy-3,7,3'-trimethoxyflavone (10) showed weak activity against Plasmodium falciparum.

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