Cyclo(Pro-Leu)

CAS# 5654-86-4

Cyclo(Pro-Leu)

2D Structure

Catalog No. BCN2426----Order now to get a substantial discount!

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Quality Control of Cyclo(Pro-Leu)

3D structure

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Cyclo(Pro-Leu)

Number of papers citing our products

Chemical Properties of Cyclo(Pro-Leu)

Cas No. 5654-86-4 SDF Download SDF
PubChem ID 102892 Appearance Powder
Formula C11H18N2O2 M.Wt 210.27
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3-(2-methylpropyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
SMILES CC(C)CC1C(=O)N2CCCC2C(=O)N1
Standard InChIKey SZJNCZMRZAUNQT-UHFFFAOYSA-N
Standard InChI InChI=1S/C11H18N2O2/c1-7(2)6-8-11(15)13-5-3-4-9(13)10(14)12-8/h7-9H,3-6H2,1-2H3,(H,12,14)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Cyclo(Pro-Leu)

The Pantoea agglomerans

Biological Activity of Cyclo(Pro-Leu)

DescriptionCyclo(Pro-Leu) has brine shrimp lethality.

Protocol of Cyclo(Pro-Leu)

Structure Identification
Nat Prod Res. 2014;28(7):473-6.

A new diketopiperazine from the gorgonian coral Menella kanisa.[Pubmed: 24479814]

Chemical investigation on the gorgonian Menella kanisa collected from Beibu Gulf led to the isolation of a new diketopiperazine, named menazepine A (1), as well as three known diketopiperazines, namely cyclo(4-hydroxyprolylleucyl) (2), Cyclo(Pro-Leu) (3) and cyclo(4-hydroxyprolylphenylalanyl) (4).
METHODS AND RESULTS:
The structure of the new diketopiperazine was elucidated on the basis of extensive spectroscopic analysis and by comparing the data with those of related metabolites. Compounds 1-4 were also evaluated for brine shrimp lethality.

Cyclo(Pro-Leu) Dilution Calculator

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Cyclo(Pro-Leu) Molarity Calculator

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Preparing Stock Solutions of Cyclo(Pro-Leu)

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.7558 mL 23.779 mL 47.5579 mL 95.1158 mL 118.8948 mL
5 mM 0.9512 mL 4.7558 mL 9.5116 mL 19.0232 mL 23.779 mL
10 mM 0.4756 mL 2.3779 mL 4.7558 mL 9.5116 mL 11.8895 mL
50 mM 0.0951 mL 0.4756 mL 0.9512 mL 1.9023 mL 2.3779 mL
100 mM 0.0476 mL 0.2378 mL 0.4756 mL 0.9512 mL 1.1889 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Cyclo(Pro-Leu)

A new diketopiperazine from the gorgonian coral Menella kanisa.[Pubmed:24479814]

Nat Prod Res. 2014;28(7):473-6.

Chemical investigation on the gorgonian Menella kanisa collected from Beibu Gulf led to the isolation of a new diketopiperazine, named menazepine A (1), as well as three known diketopiperazines, namely cyclo(4-hydroxyprolylleucyl) (2), Cyclo(Pro-Leu) (3) and cyclo(4-hydroxyprolylphenylalanyl) (4). The structure of the new diketopiperazine was elucidated on the basis of extensive spectroscopic analysis and by comparing the data with those of related metabolites. Compounds 1-4 were also evaluated for brine shrimp lethality.

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