Effusanin B

CAS# 76470-16-1

Effusanin B

2D Structure

Catalog No. BCN3391----Order now to get a substantial discount!

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Quality Control of Effusanin B

3D structure

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Effusanin B

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Chemical Properties of Effusanin B

Cas No. 76470-16-1 SDF Download SDF
PubChem ID 34174831 Appearance Powder
Formula C22H30O6 M.Wt 390.5
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC(=O)OC1CCC(C2C13COC(C2O)(C45C3CCC(C4)C(=C)C5=O)O)(C)C
Standard InChIKey TZECSBJPAFKEQJ-FHEFCECDSA-N
Standard InChI InChI=1S/C22H30O6/c1-11-13-5-6-14-20-10-27-22(26,21(14,9-13)17(11)24)18(25)16(20)19(3,4)8-7-15(20)28-12(2)23/h13-16,18,25-26H,1,5-10H2,2-4H3/t13-,14+,15+,16-,18+,20-,21+,22-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Effusanin B

The herbs of Isodon japonicus

Biological Activity of Effusanin B

Description1. Effusanin B shows antibacterial activity. 2. Effusanin B exhibits DNA-damaging activity in assay which employes DNA-repair deficient (RAD 52Y) and repair proficient (RAD +) yeast strains.
TargetsAntifection

Effusanin B Dilution Calculator

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Effusanin B Molarity Calculator

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Preparing Stock Solutions of Effusanin B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5608 mL 12.8041 mL 25.6082 mL 51.2164 mL 64.0205 mL
5 mM 0.5122 mL 2.5608 mL 5.1216 mL 10.2433 mL 12.8041 mL
10 mM 0.2561 mL 1.2804 mL 2.5608 mL 5.1216 mL 6.402 mL
50 mM 0.0512 mL 0.2561 mL 0.5122 mL 1.0243 mL 1.2804 mL
100 mM 0.0256 mL 0.128 mL 0.2561 mL 0.5122 mL 0.6402 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Effusanin B

7alpha,20-epoxy-ent-kauranoids from Isodon parvifolius.[Pubmed:16643043]

J Nat Prod. 2006 Apr;69(4):645-9.

Nine new 7alpha,20-epoxy-ent-kaurane diterpenoids, parvifolines C-K (1-9), together with 12 known analogues, rabdoternin G (10), adenolin E (11), lasiodonin (12), lushanrubescensin F (13), parvifoliside (14), effusanin A (15), Effusanin B (16), effusanin E (17), taibaihenryiin A (18), shikokianin (19), maoyecrystal J (20), and the acetonide of lasiodonin (21), were isolated from the leaves of Isodon parvifolius. The structures of compounds 1-9 were determined on the basis of spectroscopic methods including extensive 1D and 2D NMR analysis. The new diterpenoids (1-9) and lasiodonin (12) were evaluated for their inhibitory activity against A549, HT-29, and K562 cell lines.

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