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Estriol 3-glucuronide

CAS# 2479-91-6

Estriol 3-glucuronide

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Quality Control of Estriol 3-glucuronide

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Chemical structure

Estriol 3-glucuronide

3D structure

Chemical Properties of Estriol 3-glucuronide

Cas No. 2479-91-6 SDF Download SDF
PubChem ID 160638 Appearance Powder
Formula C24H32O9 M.Wt 464.5
Type of Compound Steroids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,3S,4S,5R,6S)-6-[[(13S,16R,17R)-16,17-dihydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
SMILES CC12CCC3C(C1CC(C2O)O)CCC4=C3C=CC(=C4)OC5C(C(C(C(O5)C(=O)O)O)O)O
Standard InChIKey UZKIAJMSMKLBQE-WTSDUJKYSA-N
Standard InChI InChI=1S/C24H32O9/c1-24-7-6-13-12-5-3-11(32-23-19(28)17(26)18(27)20(33-23)22(30)31)8-10(12)2-4-14(13)15(24)9-16(25)21(24)29/h3,5,8,13-21,23,25-29H,2,4,6-7,9H2,1H3,(H,30,31)/t13?,14?,15?,16-,17+,18+,19-,20+,21+,23-,24+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of Estriol 3-glucuronide

Description1. Estradiol-3-glucuronide, estradiol-17beta-glucuronide, estriol-3-glucuronide , estrone glucuronide, estriol-16alpha-glucuronide, and pregnanediol-3alpha-glucuronide are immunoreactive metabolites of the major urinary estrogens, they have used to ovulation detection methods.
TargetsEstrogen receptor | Progestogen receptor

Estriol 3-glucuronide Dilution Calculator

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Estriol 3-glucuronide Molarity Calculator

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Preparing Stock Solutions of Estriol 3-glucuronide

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1529 mL 10.7643 mL 21.5285 mL 43.0571 mL 53.8213 mL
5 mM 0.4306 mL 2.1529 mL 4.3057 mL 8.6114 mL 10.7643 mL
10 mM 0.2153 mL 1.0764 mL 2.1529 mL 4.3057 mL 5.3821 mL
50 mM 0.0431 mL 0.2153 mL 0.4306 mL 0.8611 mL 1.0764 mL
100 mM 0.0215 mL 0.1076 mL 0.2153 mL 0.4306 mL 0.5382 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Estriol 3-glucuronide

Preparation of specific antisera to estrone-3-glucuronide and estriol-3-glucuronide.[Pubmed:6323874]

J Steroid Biochem. 1984 Feb;20(2):621-6.

The preparation and antigenic properties of estrone-3-glucuronide- and estriol-3-glucuronide-bovine serum albumin conjugates in which the hapten is linked to the carrier protein through an (O-carboxymethyl)oxime bridge at the C-6 position on the steroid nucleus, have been described. Antibodies raised against the two immunogens in the rabbit possessed high specificity to estrone-3-glucuronide and estriol-3-glucuronide, respectively, exhibiting little cross-reactivities with other estrogen conjugates and no cross-reactions with related steroids except for free estrogens, their 3-methyl ethers and 3-sulfates. The cross-reactive antibodies were eliminated by partial immunoadsorption on affinity chromatographic media using the estrone-3-methyl ether 17-(O-carboxymethyl)oxime- and estriol-3-methyl ether 16 (or 17)-hemisuccinate-aminohexyl Sepharose conjugates, respectively. The purified antisera exhibited no cross-reactivities with free estrogens and ring A conjugates of estrone and estriol.

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