Ethacrynic acid - d5CAS# 1330052-59-9 |
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| Cas No. | 1330052-59-9 | SDF | Download SDF |
| PubChem ID | 71316435 | Appearance | Powder |
| Formula | C13H7D5Cl2O4 | M.Wt | 308.17 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol | ||
| Chemical Name | 2-[2,3-dichloro-4-(3,3,4,4,4-pentadeuterio-2-methylidenebutanoyl)phenoxy]acetic acid | ||
| SMILES | CCC(=C)C(=O)C1=C(C(=C(C=C1)OCC(=O)O)Cl)Cl | ||
| Standard InChIKey | AVOLMBLBETYQHX-WNWXXORZSA-N | ||
| Standard InChI | InChI=1S/C13H12Cl2O4/c1-3-7(2)13(18)8-4-5-9(12(15)11(8)14)19-6-10(16)17/h4-5H,2-3,6H2,1H3,(H,16,17)/i1D3,3D2 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Deuterated ethacrynic acid. Used as an internal standard for GC- or LC-mass spectrometry. |
Ethacrynic acid - d5 Dilution Calculator
Ethacrynic acid - d5 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.245 mL | 16.2248 mL | 32.4496 mL | 64.8992 mL | 81.1241 mL |
| 5 mM | 0.649 mL | 3.245 mL | 6.4899 mL | 12.9798 mL | 16.2248 mL |
| 10 mM | 0.3245 mL | 1.6225 mL | 3.245 mL | 6.4899 mL | 8.1124 mL |
| 50 mM | 0.0649 mL | 0.3245 mL | 0.649 mL | 1.298 mL | 1.6225 mL |
| 100 mM | 0.0324 mL | 0.1622 mL | 0.3245 mL | 0.649 mL | 0.8112 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Ethacrynic acid D5 is a deuterium labeled Ethacrynic acid. Ethacrynic acid is a diuretic. Ethacrynic acid is an inhibitor of glutathione S-transferases (GSTs). Ethacrynic acid is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice.
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