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beta-D-Fructopyranose

CAS# 7660-25-5

beta-D-Fructopyranose

2D Structure

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3D structure

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beta-D-Fructopyranose

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Chemical Properties of beta-D-Fructopyranose

Cas No. 7660-25-5 SDF Download SDF
PubChem ID 24310 Appearance Powder
Formula C6H12O6 M.Wt 180
Type of Compound N/A Storage Desiccate at -20°C
Synonyms fructosteril;laevoral;laevosan
Solubility H2O : 6.8 mg/mL (37.74 mM; Need ultrasonic and warming)
Chemical Name (2R,3S,4R,5R)-2-(hydroxymethyl)oxane-2,3,4,5-tetrol
SMILES C1C(C(C(C(O1)(CO)O)O)O)O
Standard InChIKey LKDRXBCSQODPBY-ARQDHWQXSA-N
Standard InChI InChI=1S/C6H12O6/c7-2-6(11)5(10)4(9)3(8)1-12-6/h3-5,7-11H,1-2H2/t3-,4-,5+,6-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

beta-D-Fructopyranose Dilution Calculator

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beta-D-Fructopyranose Molarity Calculator

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Preparing Stock Solutions of beta-D-Fructopyranose

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.5556 mL 27.7778 mL 55.5556 mL 111.1111 mL 138.8889 mL
5 mM 1.1111 mL 5.5556 mL 11.1111 mL 22.2222 mL 27.7778 mL
10 mM 0.5556 mL 2.7778 mL 5.5556 mL 11.1111 mL 13.8889 mL
50 mM 0.1111 mL 0.5556 mL 1.1111 mL 2.2222 mL 2.7778 mL
100 mM 0.0556 mL 0.2778 mL 0.5556 mL 1.1111 mL 1.3889 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on beta-D-Fructopyranose

High Fructose Intake During Pregnancy in Rats Influences the Maternal Microbiome and Gut Development in the Offspring.[Pubmed:29971089]

Front Genet. 2018 Jun 19;9:203.

Studies in pregnant women indicate the maternal microbiome changes during pregnancy so as to benefit the mother and fetus. In contrast, disruption of the maternal microbiota around birth can compromise normal bacterial colonisation of the infant's gastrointestinal tract. This may then inhibit development of the gut so as to increase susceptibility to inflammation and reduce barrier function. The impact of modulating fructose intake on the maternal microbiome through pregnancy is unknown, therefore we examined the effect of fructose supplementation on the maternal microbiome together with the immediate and next generation effects in the offspring. Wistar rat dams were divided into control and fructose fed groups that received 10% fructose in their drinking water from 8 weeks of age and throughout pregnancy (10-13 weeks). Maternal fecal and blood samples were collected pre-mating (9 weeks) and during early (gestational day 4-7) and late pregnancy (gestational day 19-21). We show supplementation of the maternal diet with fructose appears to significantly modulate the maternal microbiome, with a significant reduction in Lactobacillus and Bacteroides. In offspring maintained on this diet up to pregnancy and term there was a reduction in gene expression of markers of gut barrier function that could adversely affect its function. An exacerbated insulin response to pregnancy, reduced birth weight, but increased fat mass was also observed in these offspring. In conclusion dietary supplementation with fructose modulates the maternal microbiome in ways that could adversely affect fetal growth and later gut development.

Description

Fructose is a simple ketonic monosaccharide found in many plants, where it is often bonded to glucose to form the disaccharide sucrose.

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