Heteroclitin ACAS# 140369-75-1 |
Quality Control & MSDS
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| Cas No. | 140369-75-1 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C28H36O8 | M.Wt | 500.58 |
| Type of Compound | Lignanoids | Storage | Desiccate at -20°C |
| Synonyms | (+)-Heteroclitin A | ||
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Heteroclitin A Dilution Calculator
Heteroclitin A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.9977 mL | 9.9884 mL | 19.9768 mL | 39.9537 mL | 49.9421 mL |
| 5 mM | 0.3995 mL | 1.9977 mL | 3.9954 mL | 7.9907 mL | 9.9884 mL |
| 10 mM | 0.1998 mL | 0.9988 mL | 1.9977 mL | 3.9954 mL | 4.9942 mL |
| 50 mM | 0.04 mL | 0.1998 mL | 0.3995 mL | 0.7991 mL | 0.9988 mL |
| 100 mM | 0.02 mL | 0.0999 mL | 0.1998 mL | 0.3995 mL | 0.4994 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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New lignans and cytotoxic constituents from Schisandra propinqua.[Pubmed:16491454]
Planta Med. 2006 Feb;72(2):169-74.
The CHCl (3) extract from the stems of Schisandra propinqua (Wall.) Baill exhibited significant cytotoxic activity against cancer cell lines. Subsequent fractionation procedures led to the isolation of four new dibenzocyclooctadiene lignans, propinquanins A - D, along with two known lignans, schisantherin I and Heteroclitin A, and three known triterpenoids, isoschisandrolic acid, schisandrolic acid and schisandronic acid. Their structures, including absolute stereochemistry, were elucidated through analyses of NMR data and CD spectra. The isolated compounds were tested for their cytotoxic activity in several tumor cell lines with the MTT assay. Propinquanin B ( 2) was significantly cytotoxic (IC (50) values < 10 microM) in HL-60 and Hep-G2 tumor cell lines. Cell cycle analysis and Hoechst 33 258 staining assay suggested that one possible mechanism of cytotoxic activity by 2 might be related to the induction of apoptosis.
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