Kif15-IN-2CAS# 672926-33-9 |
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Quality Control & MSDS
3D structure
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| Cas No. | 672926-33-9 | SDF | Download SDF |
| PubChem ID | 60076305 | Appearance | Powder |
| Formula | C20H20N6O4S | M.Wt | 440.48 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | DMSO : 20 mg/mL (45.41 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble) | ||
| Chemical Name | (2S)-2-(2,4-dioxo-1H-quinazolin-3-yl)-3-methyl-N-[4-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)-1,3-thiazol-2-yl]butanamide | ||
| SMILES | CC1=C(SC(=N1)NC(=O)C(C(C)C)N2C(=O)C3=CC=CC=C3NC2=O)C4=NN=C(O4)C | ||
| Standard InChIKey | OHVKUJISCPKSER-AWEZNQCLSA-N | ||
| Standard InChI | InChI=1S/C20H20N6O4S/c1-9(2)14(26-18(28)12-7-5-6-8-13(12)22-20(26)29)16(27)23-19-21-10(3)15(31-19)17-25-24-11(4)30-17/h5-9,14H,1-4H3,(H,22,29)(H,21,23,27)/t14-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Kif15-IN-2 is an inhibitor of the mitotic kinesin Kif15, and is used for the research of cellular proliferative diseases.In Vitro:Kif15-IN-2 (Compound 14) is an inhibitor of the mitotic kinesin Hs Kif15, with the potential activities against cellular proliferative diseases such as cancer, hyperplasias, restenosis, cardiac hypertrophy, immune disorders and inflammation[1]. References: | |||||
Kif15-IN-2 Dilution Calculator
Kif15-IN-2 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.2703 mL | 11.3513 mL | 22.7025 mL | 45.405 mL | 56.7563 mL |
| 5 mM | 0.4541 mL | 2.2703 mL | 4.5405 mL | 9.081 mL | 11.3513 mL |
| 10 mM | 0.227 mL | 1.1351 mL | 2.2703 mL | 4.5405 mL | 5.6756 mL |
| 50 mM | 0.0454 mL | 0.227 mL | 0.4541 mL | 0.9081 mL | 1.1351 mL |
| 100 mM | 0.0227 mL | 0.1135 mL | 0.227 mL | 0.4541 mL | 0.5676 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Kif15-IN-2 is a potent Kif15 kinesin inhibitor; inhibits cellular proliferation in tumor cell lines.
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Kif15-IN-2 is an inhibitor of the mitotic kinesin Kif15, and is used for the research of cellular proliferative diseases.
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