LaetanineCAS# 72361-67-2 |
Quality Control & MSDS
3D structure
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Number of papers citing our products
| Cas No. | 72361-67-2 | SDF | Download SDF |
| PubChem ID | 129371873 | Appearance | Powder |
| Formula | C18H19NO4 | M.Wt | 313.35 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (6aS)-1,9-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10-diol | ||
| SMILES | COC1=C(C=C2C(=C1)CC3C4=C2C(=C(C=C4CCN3)O)OC)O | ||
| Standard InChIKey | URQAEFLEDPPPFX-LBPRGKRZSA-N | ||
| Standard InChI | InChI=1S/C18H19NO4/c1-22-15-7-10-5-12-16-9(3-4-19-12)6-14(21)18(23-2)17(16)11(10)8-13(15)20/h6-8,12,19-21H,3-5H2,1-2H3/t12-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Structure Identification | Masters thesis,2009, University of Malaya.Alkaloids isolated from litsea petiolata and phoebe tavoyana (Lauraceae).[Reference: WebLink]A study on the alkaloidal composition of two Malaysian plants from the family of Lauraceae i.e Litsea petiolata Hk.F and Phoebe tavoyana (Meissn.) Hk.F., has been carried out.
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Laetanine Dilution Calculator
Laetanine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.1913 mL | 15.9566 mL | 31.9132 mL | 63.8264 mL | 79.783 mL |
| 5 mM | 0.6383 mL | 3.1913 mL | 6.3826 mL | 12.7653 mL | 15.9566 mL |
| 10 mM | 0.3191 mL | 1.5957 mL | 3.1913 mL | 6.3826 mL | 7.9783 mL |
| 50 mM | 0.0638 mL | 0.3191 mL | 0.6383 mL | 1.2765 mL | 1.5957 mL |
| 100 mM | 0.0319 mL | 0.1596 mL | 0.3191 mL | 0.6383 mL | 0.7978 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Aporphine alkaloids with in vitro antiplasmodial activity from the leaves of Phoebe tavoyana.[Pubmed:30897964]
J Asian Nat Prod Res. 2019 Mar 21:1-9.
One new aporphine named tavoyanine A (1), along with four known aporphines Laetanine (2), roemerine (3), laurolitsine (4), and boldine (5), and one morphinandienone type sebiferine (6) were isolated from the leaves of Phoebe tavoyana (Meissn.) Hook f. (Lauraceae). The isolation was achieved by chromatographic techniques, and the structural elucidation was performed via spectral methods. This paper also reports the antiplasmodial activity of roemerine (3), laurolitsine (4), boldine (5), and sebiferine (6). The results showed that 3-6 have a potent inhibitory activity against the growth of Plasmodium falciparum 3D7 clone, with IC50 values of 0.89, 1.49, 1.65, and 2.76 microg/ml, respectively.
