Laetanine

CAS# 72361-67-2

Laetanine

Catalog No. BCN8623----Order now to get a substantial discount!

Product Name & Size Price Stock
Laetanine: 5mg Please Inquire In Stock
Laetanine: 10mg Please Inquire In Stock
Laetanine: 20mg Please Inquire Please Inquire
Laetanine: 50mg Please Inquire Please Inquire
Laetanine: 100mg Please Inquire Please Inquire
Laetanine: 200mg Please Inquire Please Inquire
Laetanine: 500mg Please Inquire Please Inquire
Laetanine: 1000mg Please Inquire Please Inquire

Quality Control of Laetanine

Number of papers citing our products

Chemical structure

Laetanine

3D structure

Chemical Properties of Laetanine

Cas No. 72361-67-2 SDF Download SDF
PubChem ID 129371873 Appearance Powder
Formula C18H19NO4 M.Wt 313.35
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (6aS)-1,9-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10-diol
SMILES COC1=C(C=C2C(=C1)CC3C4=C2C(=C(C=C4CCN3)O)OC)O
Standard InChIKey URQAEFLEDPPPFX-LBPRGKRZSA-N
Standard InChI InChI=1S/C18H19NO4/c1-22-15-7-10-5-12-16-9(3-4-19-12)6-14(21)18(23-2)17(16)11(10)8-13(15)20/h6-8,12,19-21H,3-5H2,1-2H3/t12-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Laetanine

The herbs of Litsea laeta

Protocol of Laetanine

Structure Identification
Masters thesis,2009, University of Malaya.

Alkaloids isolated from litsea petiolata and phoebe tavoyana (Lauraceae).[Reference: WebLink]

A study on the alkaloidal composition of two Malaysian plants from the family of Lauraceae i.e Litsea petiolata Hk.F and Phoebe tavoyana (Meissn.) Hk.F., has been carried out.
METHODS AND RESULTS:
The alkaloids were extracted with dichloromethane, whereas the isolation of the alkaloids was achieved by various chromatographic techniques such as column chromatography and preparative thin layer chromatography. A total of 14 compounds were isolated of which two are new alkaloids. The structural elucidations were carried out via spectroscopic methods; notably 1D and 2D NMR (COSY, HMQC, HMBC, NOE-DIFF), MS, IR, UV and comparison with the published data. Investigation of the alkaloidal content from the bark of Litsea petiolata afforded five alkaloids. Compounds isolated are two indole alkaloids (Î2-carboline) namely Harman or aribine 52, norharman 53, along with the three known isoquinoline alkaloids which normally occur in Lauraceae plant; Benzylisoquinolines: reticuline 31, aporphine: isoboldine 61; and one simple isoquinoline: thalifoline 100. Î2-carboline alkaloid: Harman and norharman type were isolated for the first time in the genus of Litsea.
CONCLUSIONS:
Isolation and purification of alkaloids from the bark of Phoebe tavoyana afforded 9 alkaloids of which 2 are new compounds: (+)-tavoyanine 101 and (-)-tavoyanine 102 along with four known aporphines; norboldine 77, Laetanine 73, roemerine 84, boldine 74 and one morphinandienone, sebiferine 103.

Laetanine Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Laetanine Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Laetanine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1913 mL 15.9566 mL 31.9132 mL 63.8264 mL 79.783 mL
5 mM 0.6383 mL 3.1913 mL 6.3826 mL 12.7653 mL 15.9566 mL
10 mM 0.3191 mL 1.5957 mL 3.1913 mL 6.3826 mL 7.9783 mL
50 mM 0.0638 mL 0.3191 mL 0.6383 mL 1.2765 mL 1.5957 mL
100 mM 0.0319 mL 0.1596 mL 0.3191 mL 0.6383 mL 0.7978 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Laetanine

Aporphine alkaloids with in vitro antiplasmodial activity from the leaves of Phoebe tavoyana.[Pubmed:30897964]

J Asian Nat Prod Res. 2019 Mar 21:1-9.

One new aporphine named tavoyanine A (1), along with four known aporphines Laetanine (2), roemerine (3), laurolitsine (4), and boldine (5), and one morphinandienone type sebiferine (6) were isolated from the leaves of Phoebe tavoyana (Meissn.) Hook f. (Lauraceae). The isolation was achieved by chromatographic techniques, and the structural elucidation was performed via spectral methods. This paper also reports the antiplasmodial activity of roemerine (3), laurolitsine (4), boldine (5), and sebiferine (6). The results showed that 3-6 have a potent inhibitory activity against the growth of Plasmodium falciparum 3D7 clone, with IC50 values of 0.89, 1.49, 1.65, and 2.76 microg/ml, respectively.

Description

Laetanine, a noraporphine alkaloid from Litsea laeta, exhibits antiplasmodial activity.

Keywords:

Laetanine,72361-67-2,Natural Products, buy Laetanine , Laetanine supplier , purchase Laetanine , Laetanine cost , Laetanine manufacturer , order Laetanine , high purity Laetanine

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: