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Periplocoside M

CAS# 116782-73-1

Periplocoside M

2D Structure

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Quality Control of Periplocoside M

3D structure

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Periplocoside M

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Chemical Properties of Periplocoside M

Cas No. 116782-73-1 SDF Download SDF
PubChem ID 134715182 Appearance Powder
Formula C34H52O9 M.Wt 604.78
Type of Compound Steroids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,6R)-6-[[(3S,8R,9S,10R,13S,14S,17R)-17-[(1S)-1-[(2R,4S,5S,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxyethyl]-17-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl]oxy]-4-methoxy-2-methyl-2H-pyran-5-one
SMILES CC1C=C(C(=O)C(O1)OC2CCC3(C4CCC5(C(C4CC=C3C2)CCC5(C(C)OC6CC(C(C(O6)C)O)O)O)C)C)OC
Standard InChIKey CGUNKFNCRCGQRL-ZECAFWDFSA-N
Standard InChI InChI=1S/C34H52O9/c1-18-15-27(39-6)30(37)31(40-18)43-22-9-12-32(4)21(16-22)7-8-23-24(32)10-13-33(5)25(23)11-14-34(33,38)20(3)42-28-17-26(35)29(36)19(2)41-28/h7,15,18-20,22-26,28-29,31,35-36,38H,8-14,16-17H2,1-6H3/t18-,19-,20-,22-,23+,24-,25-,26-,28+,29+,31-,32-,33-,34-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Periplocoside M

The roots of Periploca sepium Bge.

Biological Activity of Periplocoside M

Description1. Periplocoside M possesses observably antitumor activity against SMMC-7721( IC 50=12.9 ng/L),Hela( IC 50=8.63 ng/L) and MCF-7( IC 50=18.5 ng/L) cancer cell lines.

Periplocoside M Dilution Calculator

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Periplocoside M Molarity Calculator

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Preparing Stock Solutions of Periplocoside M

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6535 mL 8.2675 mL 16.5349 mL 33.0699 mL 41.3373 mL
5 mM 0.3307 mL 1.6535 mL 3.307 mL 6.614 mL 8.2675 mL
10 mM 0.1653 mL 0.8267 mL 1.6535 mL 3.307 mL 4.1337 mL
50 mM 0.0331 mL 0.1653 mL 0.3307 mL 0.6614 mL 0.8267 mL
100 mM 0.0165 mL 0.0827 mL 0.1653 mL 0.3307 mL 0.4134 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Periplocoside M

[A new cardiac glycoside from Periploca forrestii].[Pubmed:23189735]

Zhongguo Zhong Yao Za Zhi. 2012 Aug;37(15):2286-8.

OBJECTIVE: To study the chemical constituents of Periploca forrestii. METHOD: The constituents were separate using such various column chromatographic techniques as silica gel, RP-18 silica gel, MCI and Sephadex LH-20. Their structures were identified by such methods as spectral analysis. RESULT: Ten compounds were isolated and identified as periforgenin A-3-O-beta-digitoxopyranoside (1), beta-sitosterol (2), periforoside I (3), ursolic acid (4), periplogenin (5), periplocin (6), glycoside E (7), Periplocoside M (8) , daucosterol (9), 2alpha, 3alpha, 23-trihydroxy-urs-12-en-28-oic acid (10). CONCLUSION: Compound 1 was a new cardiac glycoside and compound 8 was reported for the first time from this plant.

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