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Magnoflorine Iodide

CAS# 4277-43-4

Magnoflorine Iodide

Catalog No. BCN2911----Order now to get a substantial discount!

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Magnoflorine Iodide: 5mg $92 In Stock
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Quality Control of Magnoflorine Iodide

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Chemical structure

Magnoflorine Iodide

3D structure

Chemical Properties of Magnoflorine Iodide

Cas No. 4277-43-4 SDF Download SDF
PubChem ID 6451920 Appearance Powder
Formula C20H24INO4 M.Wt 469.31
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (6aS)-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-ium-1,11-diol;iodide
SMILES C[N+]1(CCC2=CC(=C(C3=C2C1CC4=C3C(=C(C=C4)OC)O)O)OC)C.[I-]
Standard InChIKey ODRHNGNRVVELAJ-ZOWNYOTGSA-N
Standard InChI InChI=1S/C20H23NO4.HI/c1-21(2)8-7-12-10-15(25-4)20(23)18-16(12)13(21)9-11-5-6-14(24-3)19(22)17(11)18;/h5-6,10,13H,7-9H2,1-4H3,(H-,22,23);1H/t13-;/m0./s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Magnoflorine Iodide

The flower of Magnolia liliiflora Desr.

Protocol of Magnoflorine Iodide

Structure Identification
J Herb Pharmacother. 2002;2(2):1-10.

Alkaloids of Thalictrum angustifolium.[Pubmed: 15277092]


METHODS AND RESULTS:
Fractionation and chromatography of the ethanolic extract of the roots of Thalictrum angustifolium L. (Ranunculaceae) afforded five alkaloids: noroxyhydrastinine (1), O-methylthalicberine (2), berberine iodide (3), jatrorrhizine iodide (4), Magnoflorine Iodide (5). In addition, one simple aromatic compound, methyl-4-hydroxybenzoate (6), was also isolated. These compounds were identified via comparison of their spectral data with authentic compounds or spectra available within our laboratory.
CONCLUSIONS:
This is the first reported isolation of these compounds from this species.

Magnoflorine Iodide Dilution Calculator

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Magnoflorine Iodide Molarity Calculator

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Preparing Stock Solutions of Magnoflorine Iodide

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1308 mL 10.6539 mL 21.3079 mL 42.6158 mL 53.2697 mL
5 mM 0.4262 mL 2.1308 mL 4.2616 mL 8.5232 mL 10.6539 mL
10 mM 0.2131 mL 1.0654 mL 2.1308 mL 4.2616 mL 5.327 mL
50 mM 0.0426 mL 0.2131 mL 0.4262 mL 0.8523 mL 1.0654 mL
100 mM 0.0213 mL 0.1065 mL 0.2131 mL 0.4262 mL 0.5327 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Magnoflorine Iodide

Alkaloids of Thalictrum angustifolium.[Pubmed:15277092]

J Herb Pharmacother. 2002;2(2):1-10.

Fractionation and chromatography of the ethanolic extract of the roots of Thalictrum angustifolium L. (Ranunculaceae) afforded five alkaloids: noroxyhydrastinine (1), O-methylthalicberine (2), berberine iodide (3), jatrorrhizine iodide (4), Magnoflorine Iodide (5). In addition, one simple aromatic compound, methyl-4-hydroxybenzoate (6), was also isolated. These compounds were identified via comparison of their spectral data with authentic compounds or spectra available within our laboratory. This is the first reported isolation of these compounds from this species.

Description

(+)-Magnoflorine iodide (Magnoflorine iodide), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm. (+)-Magnoflorine iodide has anti-fungal, anti-antidiabetic and anti-oxidative activity.

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