NeoolivilCAS# 1277182-38-3 |
Quality Control & MSDS
Package In Stock
Number of papers citing our products
| Cas No. | 1277182-38-3 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C20H24O7 | M.Wt | 376.44 |
| Type of Compound | Lignans | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Neoolivil Dilution Calculator
Neoolivil Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.6565 mL | 13.2823 mL | 26.5647 mL | 53.1293 mL | 66.4116 mL |
| 5 mM | 0.5313 mL | 2.6565 mL | 5.3129 mL | 10.6259 mL | 13.2823 mL |
| 10 mM | 0.2656 mL | 1.3282 mL | 2.6565 mL | 5.3129 mL | 6.6412 mL |
| 50 mM | 0.0531 mL | 0.2656 mL | 0.5313 mL | 1.0626 mL | 1.3282 mL |
| 100 mM | 0.0266 mL | 0.1328 mL | 0.2656 mL | 0.5313 mL | 0.6641 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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[Lignans from barks of Ailanthus altissima].[Pubmed:28936846]
Zhongguo Zhong Yao Za Zhi. 2016 Dec;41(24):4615-4620.
Eleven lignans were isolated from the ethanol extract of the barks of Ailanthus altissima through various column chromatography methods including silica gel, Sephadex LH-20, ODS and HPLC. By physical, chemical and comprehensive spectroscopic methods, their structures were identified as (+)-Neoolivil(1), prunustosanan AI (2), (7S,8R)-guaiacyl-glycerol-beta-O-4'-neolignan (3), (7R,8S)-guaiacyl-glycerol-beta-O-4'-neolignan (4), (7S,8R)-1-(4-hydroxy-3-methoxyphenyl)-2-[4-(3-hydroxypropyl)-2,6-dimethoxyphenoxy]-1,3-propanediol(5), pinnatifidanin B V (6), pinnatifidanin B VI (7), (7R,7'R,7''S,8S,8'S,8''S)-4',4''-dihydroxy-3,3',3'',5-tetramethoxy-7,9':7',9-diepoxy-4,8''-oxy-8,8'-sesquineolignan-7'',9''-diol (8), hedyotol D (9), 5-(2-propenyl)-7-methoxy-2-(3,4-methylenediovxyphenyl)benzofuran (10), and (7R,8S,7'E)-guaiacyl-glycerol-beta-O-4'-sinapyl ether(11).All of these compounds were isolated from this plant for the first time.
Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG).[Pubmed:9434605]
Planta Med. 1997 Dec;63(6):529-32.
Polar extracts of the stinging nettle (Urtica dioica L.) roots contain the ligans (+)-Neoolivil, (-)-secoisolariciresinol, dehydrodiconiferyl alcohol, isolariciresinol, pinoresinol, and 3,4-divanillyltetrahydrofuran. These compounds were either isolated from Urtica roots, or obtained semisynthetically. Their affinity to human sex hormone binding globulin (SHBG) was tested in an in vitro assay. In addition, the main intestinal transformation products of plant lignans in humans, enterodiol and enterolactone, together with enterofuran were checked for their activity. All lignans except (-)-pinoresinol developed a binding affinity to SHBG in the in vitro assay. The affinity of (-)-3,4-divanillyltetrahydrofuran was outstandingly high. These findings are discussed with respect to potential beneficial effects of plant lignans on benign prostatic hyperplasia (BPH).
