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Paeoniflorgenin

CAS# 697300-41-7

Paeoniflorgenin

Catalog No. BCX1515----Order now to get a substantial discount!

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Paeoniflorgenin: 5mg Please Inquire In Stock
Paeoniflorgenin: 10mg Please Inquire In Stock
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Quality Control of Paeoniflorgenin

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Chemical structure

Paeoniflorgenin

3D structure

Chemical Properties of Paeoniflorgenin

Cas No. 697300-41-7 SDF Download SDF
PubChem ID 73157961.0 Appearance Powder
Formula C17H18O6 M.Wt 318.32
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (3,6-dihydroxy-8-methyl-9,10-dioxatetracyclo[4.3.1.02,5.03,8]decan-2-yl)methyl benzoate
SMILES CC12CC3(C4CC1(C4(C(O2)O3)COC(=O)C5=CC=CC=C5)O)O
Standard InChIKey GWQHMWOOQLVRLG-UHFFFAOYSA-N
Standard InChI InChI=1S/C17H18O6/c1-14-8-16(19)11-7-17(14,20)15(11,13(22-14)23-16)9-21-12(18)10-5-3-2-4-6-10/h2-6,11,13,19-20H,7-9H2,1H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Paeoniflorgenin

Paeonia lactiflora

Paeoniflorgenin Dilution Calculator

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Paeoniflorgenin Molarity Calculator

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Preparing Stock Solutions of Paeoniflorgenin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1415 mL 15.7075 mL 31.4149 mL 62.8299 mL 78.5373 mL
5 mM 0.6283 mL 3.1415 mL 6.283 mL 12.566 mL 15.7075 mL
10 mM 0.3141 mL 1.5707 mL 3.1415 mL 6.283 mL 7.8537 mL
50 mM 0.0628 mL 0.3141 mL 0.6283 mL 1.2566 mL 1.5707 mL
100 mM 0.0314 mL 0.1571 mL 0.3141 mL 0.6283 mL 0.7854 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Paeoniflorgenin

A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats.[Pubmed:14750027]

Planta Med. 2003 Dec;69(12):1113-8.

Paeoniflorin is a bioactive monoterpene glucoside in Paeoniae Radix (PR), the roots of Paeonia lactiflora (Ranunculaceae). By oral administration to rats with the decoction of PR, the metabolism and pharmacokinetics of paeoniflorin were investigated in this study. A deglucosylated metabolite of paeoniflorin, Paeoniflorgenin (PG), in serum was identified based on HPLC/MS and NMR spectral data. HPLC/UV methods were developed for determining PG in serum and feces suspension. A non-compartment model was used for the calculation of pharmacokinetic parameters. Moreover, the metabolism of paeoniflorin by various types of feces was investigated as well. The paeoniflorin levels in serum were below the detection limit throughout the study. The C (max), t (max), and AUC (0-t) of PG were 8.0 microg/mL, 10 min and 487.0 microg min/mL, respectively. Paeoniflorin was found to be hydrolyzed into PG through incubation with feces of rabbit, rat, pig or human. Similar profiles of PG were shown for various types of feces, except for rabbit. In conclusion, paeoniflorin was not absorbed per se, whereas its aglycone Paeoniflorgenin was absorbable and circulating in the bloodstream. Rat and pig are appropriate models for investigating the metabolism and pharmacokinetics of paeoniflorin.

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