PodophyllolCAS# 78339-51-2 |
Quality Control & MSDS
Package In Stock
Number of papers citing our products
| Cas No. | 78339-51-2 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C22H26O8 | M.Wt | 418.44 |
| Type of Compound | Lignans | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Structure Identification | J Pharm Sci. 1983 Oct;72(10):1158-61.Antitumor agents LXII: Synthesis and biological evaluation of podophyllotoxin esters and related derivatives[Pubmed: 6644563 ]
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Podophyllol Dilution Calculator
Podophyllol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.3898 mL | 11.9491 mL | 23.8983 mL | 47.7966 mL | 59.7457 mL |
| 5 mM | 0.478 mL | 2.3898 mL | 4.7797 mL | 9.5593 mL | 11.9491 mL |
| 10 mM | 0.239 mL | 1.1949 mL | 2.3898 mL | 4.7797 mL | 5.9746 mL |
| 50 mM | 0.0478 mL | 0.239 mL | 0.478 mL | 0.9559 mL | 1.1949 mL |
| 100 mM | 0.0239 mL | 0.1195 mL | 0.239 mL | 0.478 mL | 0.5975 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antitumor agents LXII: synthesis and biological evaluation of podophyllotoxin esters and related derivatives.[Pubmed:6644563]
J Pharm Sci. 1983 Oct;72(10):1158-61.
Synthetic esters of the C-4 hydroxyl group of podophyllotoxin (I) were prepared. In addition, esters were synthesized using the diol system of tetrahydropyranyl Podophyllol (XV), produced by reducing the lactone ring of tetrahydropyranyl podophyllotoxin with lithium aluminum hydride. Six compounds, the acrylate (IV), 3,3-dimethyl acrylate (V), phenoxyacetate (IX), and ethyl adipate (XI) of I as well as Podophyllol (XIV) and tetrahydropyranyl Podophyllol dimesylate (XVIII), showed significant activity when tested using the P-388 lymphocytic leukemia screen at 3 mg/kg/day. None of the esters showed higher activity than that shown by the parent molecule I when tested at the same dosage level.
