Celosin ICAS# 1807732-38-2 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
| Cas No. | 1807732-38-2 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C53H82O24 | M.Wt | 1103.2 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Celosin H, celosin I, and celosin J could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibited significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice. |
| In vivo | Novel triterpenoid saponins from the seeds of Celosia argentea L.[Pubmed: 23157342 ]Nat Prod Res. 2013 Aug;27(15):1353-60.
|
| Structure Identification | J Asian Nat Prod Res. 2014;16(3):240-7.New oleanane-type triterpenoid saponins isolated from the seeds of Celosia argentea.[Pubmed: 24456247]
|
Celosin I Dilution Calculator
Celosin I Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 0.9065 mL | 4.5323 mL | 9.0645 mL | 18.1291 mL | 22.6613 mL |
| 5 mM | 0.1813 mL | 0.9065 mL | 1.8129 mL | 3.6258 mL | 4.5323 mL |
| 10 mM | 0.0906 mL | 0.4532 mL | 0.9065 mL | 1.8129 mL | 2.2661 mL |
| 50 mM | 0.0181 mL | 0.0906 mL | 0.1813 mL | 0.3626 mL | 0.4532 mL |
| 100 mM | 0.0091 mL | 0.0453 mL | 0.0906 mL | 0.1813 mL | 0.2266 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Hamaudol
Catalog No.:BCN6371
CAS No.:735-46-6
- N-Benzyloctadecanamide
Catalog No.:BCN8725
CAS No.:5327-45-7
- 3-O-Acetyl-20-hydroxyecdysone
Catalog No.:BCN8728
CAS No.:22961-68-8
- Pseudolaric acid C2
Catalog No.:BCN8726
CAS No.:82508-35-8
- Trikamsteroside C
Catalog No.:BCN8724
CAS No.:952579-35-0
- Oleuroside
Catalog No.:BCN8722
CAS No.:116383-31-4
- Dihydrowithaferin A
Catalog No.:BCN8721
CAS No.:5589-41-3
- 19 alpha-Hydroxyasiatic acid
Catalog No.:BCN8720
CAS No.:70868-78-9
- 3-Methylxanthine
Catalog No.:BCN8719
CAS No.:1076-22-8
- Nagarine
Catalog No.:BCN8718
CAS No.:41849-35-8
- 1-Isomangostin
Catalog No.:BCN8717
CAS No.:19275-44-6
- Indole-3-acetic acid
Catalog No.:BCN8716
CAS No.:87-51-4
- Polygalin C
Catalog No.:BCN8738
CAS No.:934768-05-5
- Lucidenic acid F
Catalog No.:BCN6374
CAS No.:98665-18-0
- Irilone
Catalog No.:BCN8188
CAS No.:41653-81-0
- Trikamsteroside D
Catalog No.:BCN8610
CAS No.:952579-36-1
- Podophyllol
Catalog No.:BCN6372
CAS No.:78339-51-2
- Parispseudoside C
Catalog No.:BCN8737
CAS No.:1206707-59-6
- 3'-Hydroxymirificin
Catalog No.:BCN6365
CAS No.:168035-02-7
- Soyasapogenol C
Catalog No.:BCN6388
CAS No.:595-14-2
- Zerumbone
Catalog No.:BCN6363
CAS No.:471-05-6
- 1,3,6-Trihydroxy-2-methylanthraquinone 3-O-(6'-O-acetyl)-alpha-L-rhamnosyl-(1->2)-Beta-D-glucoside
Catalog No.:BCN6384
CAS No.:87686-87-1
- Luteolin-4'-O-glucoside
Catalog No.:BCN8734
CAS No.:6920-38-3
- Guvacine
Catalog No.:BCN6529
CAS No.:498-96-4
Dereplication-guided isolation of novel hepatoprotective triterpenoid saponins from Celosiae Semen by high-performance liquid chromatography coupled with electrospray ionization tandem quadrupole-time-of-flight mass spectrometry.[Pubmed:27721071]
J Pharm Biomed Anal. 2017 Jan 5;132:148-155.
Although natural products (NPs) from ethnomedical plants have played a vital role in modern drug discovery, separation and purification of bioactive compounds from plant extract is still challenging. In this study, a dereplication strategy using HPLC-QTOF-MS was employed to rapidly discover and highly targeted isolate the novel hepatoprotective triterpenoid saponins from the methanol extract of Celosiae Semen. Firstly, four known saponins, i.e. celosin H, Celosin I, celosin J, and pseudoginsenoside RT1 were selected as model compounds, and their fragmentation patterns in ESI-QTOF-MS/MS were characterized. Secondly, an HPLC-QTOF-MS/MS method was applied to chemically screen the saponins of interest, and thereby to guide the subsequent fraction and isolation procedure. Thirdly, the targeted isolation of desired compounds afforded two new triterpenoid saponins namely celosin K (1) and celosin L (2), which were structurally elucidated by combination of extensive NMR spectroscopic and chemical analyses. Finally, the protective effects of compounds 1 and 2 against APAP-induced hepatotoxicity in HepG2 cells were evaluated. These results indicate that the HPLC-QTOF-MS-guided isolation is an efficient methodology for isolating new NPs from medicinal plants through improving selectivity in separation and purification process.
Novel triterpenoid saponins from the seeds of Celosia argentea L.[Pubmed:23157342]
Nat Prod Res. 2013 Aug;27(15):1353-60.
Two new triterpenoid saponins Celosin I (1) and Celosin II (2) were isolated from the seeds of Celosia argentea L. (Amaranthaceae). The structures of the two new compounds were elucidated based on chemical analysis and spectral methods (IR, 1-D and 2-D NMR, ESI-MS, HR-ESI-MS). They exhibited significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice.
