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Rauvovertine C

CAS# 2055073-74-8

Rauvovertine C

Catalog No. BCN7727----Order now to get a substantial discount!

Product Name & Size Price Stock
Rauvovertine C: 5mg $1064 In Stock
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Quality Control of Rauvovertine C

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Chemical structure

Rauvovertine C

3D structure

Chemical Properties of Rauvovertine C

Cas No. 2055073-74-8 SDF Download SDF
PubChem ID 134714912 Appearance Powder
Formula C20H23N3O M.Wt 321.41
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,13S,15R,17S,20S,21S)-17-methoxy-21-methyl-1,11,18-triazahexacyclo[11.8.0.02,16.04,12.05,10.015,20]henicosa-4(12),5,7,9,18-pentaene
SMILES CC1C2C=NC(C3C2CC4N1C3CC5=C4NC6=CC=CC=C56)OC
Standard InChIKey ZZHBMDPVMXMCCC-YBOQEZAPSA-N
Standard InChI InChI=1S/C20H23N3O/c1-10-14-9-21-20(24-2)18-12(14)7-17-19-13(8-16(18)23(10)17)11-5-3-4-6-15(11)22-19/h3-6,9-10,12,14,16-18,20,22H,7-8H2,1-2H3/t10-,12+,14+,16-,17-,18?,20-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Rauvovertine C

The stems of Rauvolfia verticillata.

Biological Activity of Rauvovertine C

Description1. Rauvovertine C shows cytotoxicity in vitro against human tumor cell lines.

Rauvovertine C Dilution Calculator

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Rauvovertine C Molarity Calculator

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Preparing Stock Solutions of Rauvovertine C

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1113 mL 15.5565 mL 31.1129 mL 62.2258 mL 77.7823 mL
5 mM 0.6223 mL 3.1113 mL 6.2226 mL 12.4452 mL 15.5565 mL
10 mM 0.3111 mL 1.5556 mL 3.1113 mL 6.2226 mL 7.7782 mL
50 mM 0.0622 mL 0.3111 mL 0.6223 mL 1.2445 mL 1.5556 mL
100 mM 0.0311 mL 0.1556 mL 0.3111 mL 0.6223 mL 0.7778 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Rauvovertine C

Hexacyclic monoterpenoid indole alkaloids from Rauvolfia verticillata.[Pubmed:26474672]

Fitoterapia. 2015 Dec;107:44-48.

Five new hexacyclic monoterpenoid indole alkaloids, rauvovertine A (1), 17-epi-rauvovertine A (2), rauvovertine B (3), 17-epi-rauvovertine B (4), and Rauvovertine C (5) together with 17 known analogues were isolated from the stems of Rauvolfia verticillata. Compounds 1/2 and 3/4 were obtained as C-17 epimeric mixtures due to rapid hemiacetal tautomerism in solution. The structures of 1-5 were established by spectroscopic analysis and with the aid of molecular modeling. The new alkaloids were evaluated for their cytotoxicity in vitro against human tumor HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines.

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