IsonardoperoxideCAS# 205248-65-3 |
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| Cas No. | 205248-65-3 | SDF | Download SDF |
| PubChem ID | 10825647 | Appearance | Oil |
| Formula | C15H22O4 | M.Wt | 266.33 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1S,5R,7S,8S)-7-hydroxy-1,5-dimethyl-8-propan-2-yl-9,10-dioxatricyclo[6.2.2.02,6]dodec-2(6)-en-3-one | ||
| SMILES | CC1CC(=O)C2=C1C(C3(CCC2(OO3)C)C(C)C)O | ||
| Standard InChIKey | BDBRZURCDWHOCK-GBALPHGKSA-N | ||
| Standard InChI | InChI=1S/C15H22O4/c1-8(2)15-6-5-14(4,18-19-15)12-10(16)7-9(3)11(12)13(15)17/h8-9,13,17H,5-7H2,1-4H3/t9-,13+,14+,15+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The roots of Nardostachys chinensis.
| Description | 1. Isonardoperoxide shows strong antimalarial activity against Plasmodium falciparum malaria (6.0 × 10−7 M). |
| Targets | Antifection |
Isonardoperoxide Dilution Calculator
Isonardoperoxide Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.7547 mL | 18.7737 mL | 37.5474 mL | 75.0948 mL | 93.8685 mL |
| 5 mM | 0.7509 mL | 3.7547 mL | 7.5095 mL | 15.019 mL | 18.7737 mL |
| 10 mM | 0.3755 mL | 1.8774 mL | 3.7547 mL | 7.5095 mL | 9.3869 mL |
| 50 mM | 0.0751 mL | 0.3755 mL | 0.7509 mL | 1.5019 mL | 1.8774 mL |
| 100 mM | 0.0375 mL | 0.1877 mL | 0.3755 mL | 0.7509 mL | 0.9387 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Novel antimalarial guaiane-type sesquiterpenoids from Nardostachys chinensis roots.
Tetrahedron Letters, 1998, 39(11):1361-1364.
Three guaiane-type sesquiterpenoids, nardoperoxide (1a), Isonardoperoxide (2a) and nardoxide (3), were isolated from Nardostachys chinensis roots. Their structures were elucidated by spectral means. Among them, two endoperoxides, nardoperoxide (1a) and Isonardoperoxide (2a), showed strong antimalarial activity against Plasmodium falciparum malaria (EC50 1.5 × 10−6 and 6.0 × 10−7 M, respectively).
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