NardosinonediolCAS# 20489-11-6 |
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| Cas No. | 20489-11-6 | SDF | Download SDF |
| PubChem ID | 134715257 | Appearance | Powder |
| Formula | C15H24O3 | M.Wt | 252.34 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (3R,4aR,5R)-3-hydroxy-4-(2-hydroxypropan-2-yl)-4a,5-dimethyl-2,3,4,5,6,7-hexahydronaphthalen-1-one | ||
| SMILES | CC1CCC=C2C1(C(C(CC2=O)O)C(C)(C)O)C | ||
| Standard InChIKey | DBDGFZLAYDIKSV-ZGEJAQKFSA-N | ||
| Standard InChI | InChI=1S/C15H24O3/c1-9-6-5-7-10-11(16)8-12(17)13(14(2,3)18)15(9,10)4/h7,9,12-13,17-18H,5-6,8H2,1-4H3/t9-,12-,13?,15+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Nardostachys jatamansi
| Description | 1. Nardosinonediol shows cytotoxic activity against P-388 cells. |
Nardosinonediol Dilution Calculator
Nardosinonediol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.9629 mL | 19.8145 mL | 39.6291 mL | 79.2581 mL | 99.0727 mL |
| 5 mM | 0.7926 mL | 3.9629 mL | 7.9258 mL | 15.8516 mL | 19.8145 mL |
| 10 mM | 0.3963 mL | 1.9815 mL | 3.9629 mL | 7.9258 mL | 9.9073 mL |
| 50 mM | 0.0793 mL | 0.3963 mL | 0.7926 mL | 1.5852 mL | 1.9815 mL |
| 100 mM | 0.0396 mL | 0.1981 mL | 0.3963 mL | 0.7926 mL | 0.9907 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Cytotoxic sesquiterpenes from Nardostachys chinensis.[Pubmed:8370115]
Chem Pharm Bull (Tokyo). 1993 Jun;41(6):1183-4.
Five cytostatic sesquiterpenes, desoxo-narchinol-A (1), nardosinone (2), debilon (3), Nardosinonediol (4) and kanshone A (5), were isolated from the roots and rhizomes of Nardostachys chinensis (Valerianaceae). The steric structure of 1 was determined by nuclear Overhauser effects (NOEs) and the exciton chirality method. All five showed cytotoxic activity against P-388 cells and the structure-activity relationship of 1 was also discussed.
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