TilbroquinolCAS# 7175-09-9 |
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| Cas No. | 7175-09-9 | SDF | Download SDF |
| PubChem ID | 65592 | Appearance | Powder |
| Formula | C10H8BrNO | M.Wt | 238.08 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | DMSO : ≥ 50 mg/mL (210.01 mM) H2O : < 0.1 mg/mL (insoluble) *"≥" means soluble, but saturation unknown. | ||
| Chemical Name | 7-bromo-5-methylquinolin-8-ol | ||
| SMILES | CC1=CC(=C(C2=C1C=CC=N2)O)Br | ||
| Standard InChIKey | JMOVFFLYGIQXMM-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C10H8BrNO/c1-6-5-8(11)10(13)9-7(6)3-2-4-12-9/h2-5,13H,1H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Tilbroquinol Dilution Calculator
Tilbroquinol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.2003 mL | 21.0013 mL | 42.0027 mL | 84.0054 mL | 105.0067 mL |
| 5 mM | 0.8401 mL | 4.2003 mL | 8.4005 mL | 16.8011 mL | 21.0013 mL |
| 10 mM | 0.42 mL | 2.1001 mL | 4.2003 mL | 8.4005 mL | 10.5007 mL |
| 50 mM | 0.084 mL | 0.42 mL | 0.8401 mL | 1.6801 mL | 2.1001 mL |
| 100 mM | 0.042 mL | 0.21 mL | 0.42 mL | 0.8401 mL | 1.0501 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Tilbroquinol is an antiprotozoal agent effective against amoebiasis. It has also been used against Vibrio cholerae.
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[In vitro sensitivity of Vibrio cholerae serotype 0:139 to an intestinal antiseptic tiliquinol-tilbroquinol combination].[Pubmed:8003903]
Bull Soc Pathol Exot. 1994;87(1):38-40.
O:139 is a new serotype of Vibrio cholerae that is not agglutinated by an O:1 antiserum but causes epidemics of cholera. Strains of O:139 serotype are resistant to O/129 compound and many antibiotics but are sensitive to tetracyclines and tiliquinol-Tilbroquinol (Intetrix). The clinical management of the patients infected with serotype O:139 is identical to that of usual choleric patients. However, the immunological difference with O:1 serotype must lead to reconsider both the diagnosis and the vaccinating strategies of cholera.
Tilbroquinol is an antiprotozoal agent effective against amoebiasis. It has also been used against Vibrio cholerae.
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