Vineridine

CAS# 3489-06-3

Vineridine

Catalog No. BCN5286----Order now to get a substantial discount!

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Number of papers citing our products

Chemical structure

Vineridine

3D structure

Chemical Properties of Vineridine

Cas No. 3489-06-3 SDF Download SDF
PubChem ID 198910 Appearance Powder
Formula C22H26N2O5 M.Wt 398.5
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name methyl (1S,4aS,5aR,6S,10aS)-6'-methoxy-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
SMILES CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=C(C=C(C=C5)OC)NC4=O
Standard InChIKey SRKHGHLMEDVZRX-PNGOUSOWSA-N
Standard InChI InChI=1S/C22H26N2O5/c1-12-15-10-24-7-6-22(17-5-4-13(27-2)8-18(17)23-21(22)26)19(24)9-14(15)16(11-29-12)20(25)28-3/h4-5,8,11-12,14-15,19H,6-7,9-10H2,1-3H3,(H,23,26)/t12-,14-,15-,19+,22-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Vineridine

The herbs of Vinca erecta

Biological Activity of Vineridine

DescriptionStandard reference

Protocol of Vineridine

Structure Identification
Chemistry of Natural Compounds,1974,10(4): 496-503.

Absolute configuration of vinerine and vineridine[Reference: WebLink]


METHODS AND RESULTS:
On the basis of an analysis of the circular dichroism and NMR spectra the absolute configuration 7R, 3R, 4S, 15S, 19S, 20S has been established for vinerine; 7S, 3R, 4S, 15S, 19S, 20S for Vineridine; and 7S, 3S, 4R, 15S, 19S, 20S for N-acetylvinerine.

Khimiya Prirodnykh Soedinenii,1966,2(4): 260–265.

The structure of vinerine and vineridine[Reference: WebLink]


METHODS AND RESULTS:
1. The epigeal part ofV. erecta gathered in the Tashkent Oblast in the early vegetation period contains a mixture of alkaloids (2.7%). Separation of the total alkaloids gave vincanine, vincanidine, vinervine, akuammine, kopsinine, pseudokopsinine, and the new bases vinerine and Vineridine. 2. The structure of vinerine has been established by a study of the IR, NMR, and mass spectra.
CONCLUSIONS:
Vineridine is isomeric with vinerine at C3 and C7. 3. A new base, hydroxyindole reserpinine, has been obtained from reserpinine.

Vineridine Dilution Calculator

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Vineridine Molarity Calculator

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Preparing Stock Solutions of Vineridine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5094 mL 12.5471 mL 25.0941 mL 50.1882 mL 62.7353 mL
5 mM 0.5019 mL 2.5094 mL 5.0188 mL 10.0376 mL 12.5471 mL
10 mM 0.2509 mL 1.2547 mL 2.5094 mL 5.0188 mL 6.2735 mL
50 mM 0.0502 mL 0.2509 mL 0.5019 mL 1.0038 mL 1.2547 mL
100 mM 0.0251 mL 0.1255 mL 0.2509 mL 0.5019 mL 0.6274 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Vineridine

Absolute configuration of vinerine and vineridine

Chemistry of Natural Compounds July 1974, Volume 10, Issue 4, pp 496-503

On the basis of an analysis of the circular dichroism and NMR spectra the absolute configuration 7R, 3R, 4S, 15S, 19S, 20S has been established for vinerine; 7S, 3R, 4S, 15S, 19S, 20S for Vineridine; and 7S, 3S, 4R, 15S, 19S, 20S for N-acetylvinerine.

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