Yadanzioside ACAS# 95258-15-4 |
Quality Control & MSDS
3D structure
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| Cas No. | 95258-15-4 | SDF | Download SDF |
| PubChem ID | 72956 | Appearance | Powder |
| Formula | C32H44O16 | M.Wt | 684.68 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC1C2CC3C45COC(C4C(C(=O)O3)OC(=O)CC(C)C)(C(C(C5C2(C=C(C1=O)OC6C(C(C(C(O6)CO)O)O)O)C)O)O)C(=O)OC | ||
| Standard InChIKey | QDQJWSSPAMZRIA-AIWMZPBQSA-N | ||
| Standard InChI | InChI=1S/C32H44O16/c1-11(2)6-17(34)48-23-25-31-10-44-32(25,29(42)43-5)26(40)22(39)24(31)30(4)8-14(18(35)12(3)13(30)7-16(31)47-27(23)41)45-28-21(38)20(37)19(36)15(9-33)46-28/h8,11-13,15-16,19-26,28,33,36-40H,6-7,9-10H2,1-5H3/t12-,13-,15+,16+,19+,20-,21+,22+,23+,24+,25+,26-,28+,30-,31+,32+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The seeds of Brucea javanica.
| Description | 1. Yadanzioside A has antileukemic activity. |
Yadanzioside A Dilution Calculator
Yadanzioside A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.4605 mL | 7.3027 mL | 14.6054 mL | 29.2107 mL | 36.5134 mL |
| 5 mM | 0.2921 mL | 1.4605 mL | 2.9211 mL | 5.8421 mL | 7.3027 mL |
| 10 mM | 0.1461 mL | 0.7303 mL | 1.4605 mL | 2.9211 mL | 3.6513 mL |
| 50 mM | 0.0292 mL | 0.1461 mL | 0.2921 mL | 0.5842 mL | 0.7303 mL |
| 100 mM | 0.0146 mL | 0.073 mL | 0.1461 mL | 0.2921 mL | 0.3651 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Seven quassinoids from Fructus Bruceae with cytotoxic effects on pancreatic adenocarcinoma cell lines.[Pubmed:21480411]
Phytother Res. 2011 Dec;25(12):1796-800.
Our previous studies showed that the alcohol extract of the fruit of Brucea javanica (Fructus Bruceae) possessed significant cytotoxicity in pancreatic adenocarcinoma cell lines. A bioassay-guided fractionation and purification resulted in the isolation and characterization of seven quassinoids including brusatol, bruceine D, bruceine H, Yadanzioside A, yadanzioside G, javanicoside C and bruceantinoside A. Among them, brusatol exhibited the most potent in vitro antipancreatic cancer action, with IC(50) values of 0.36 microm and 0.10 microm on PANC-1 and SW1990 cell lines, respectively. This is the first report on the antipancreatic adenocarcinoma activity of brusatol.
Yadanziolide A, a quassinoid glycoside from Brucea javanica, has antitumor activity.
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