Yadanziolide B

CAS# 95258-13-2

Yadanziolide B

2D Structure

Catalog No. BCN6720----Order now to get a substantial discount!

Product Name & Size Price Stock
Yadanziolide B: 5mg $989 In Stock
Yadanziolide B: 10mg Please Inquire In Stock
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Yadanziolide B: 500mg Please Inquire Please Inquire
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Quality Control of Yadanziolide B

3D structure

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Yadanziolide B

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Chemical Properties of Yadanziolide B

Cas No. 95258-13-2 SDF Download SDF
PubChem ID 11744055 Appearance Powder
Formula C20H26O11 M.Wt 442.41
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1=CC(=O)C(C2(C1C(C3C45C2C(C(C(C4(C(C(=O)O3)O)O)(OC5)CO)O)O)O)C)O
Standard InChIKey QPBBQXZJTIVCTO-VWXLKGNHSA-N
Standard InChI InChI=1S/C20H26O11/c1-6-3-7(22)12(25)17(2)8(6)9(23)15-18-5-30-19(4-21,13(26)10(24)11(17)18)20(18,29)14(27)16(28)31-15/h3,8-15,21,23-27,29H,4-5H2,1-2H3/t8-,9-,10-,11-,12-,13+,14+,15-,17+,18+,19-,20+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Yadanziolide B

The seeds of Brucea javanica.

Biological Activity of Yadanziolide B

Description1. Yadanziolide B exhibits cytotoxic activities with IC50 values of 3.00-5.81 uM.

Yadanziolide B Dilution Calculator

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Yadanziolide B Molarity Calculator

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Preparing Stock Solutions of Yadanziolide B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2603 mL 11.3017 mL 22.6035 mL 45.2069 mL 56.5087 mL
5 mM 0.4521 mL 2.2603 mL 4.5207 mL 9.0414 mL 11.3017 mL
10 mM 0.226 mL 1.1302 mL 2.2603 mL 4.5207 mL 5.6509 mL
50 mM 0.0452 mL 0.226 mL 0.4521 mL 0.9041 mL 1.1302 mL
100 mM 0.0226 mL 0.113 mL 0.226 mL 0.4521 mL 0.5651 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Yadanziolide B

Indole alkaloids and quassinoids from the stems of Brucea mollis.[Pubmed:22070654]

J Nat Prod. 2011 Nov 28;74(11):2438-45.

Seven new indole alkaloids, bruceollines H-N (1-7), three new quassinoids, yadanziolides T-V (10-12), and four known analogues, bruceolline E (8), bruceolline F (9), bruceine D (13), and Yadanziolide B (14), were isolated from an ethanol extract of the stems of Brucea mollis. The absolute configurations of compounds 2 and 5 were determined by comparison of their experimental and calculated ECD spectra. The absolute configuration of the known compound 9 was determined by using Mo2(OAc)4-induced CD analysis for the first time. Compounds 10, 13, and 14 exhibited cytotoxic activities with IC50 values of 3.00-5.81 muM.

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