Yadanziolide CCAS# 95258-12-1 |
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| Cas No. | 95258-12-1 | SDF | Download SDF |
| PubChem ID | 10409280 | Appearance | Powder |
| Formula | C20H26O9 | M.Wt | 410.41 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC1=CC(=O)C(C2(C1CC3C45C2C(C(C(C4(C(C(=O)O3)O)O)(OC5)C)O)O)C)O | ||
| Standard InChIKey | JBDMZGKDLMGOFR-CABQPPGUSA-N | ||
| Standard InChI | InChI=1S/C20H26O9/c1-7-4-9(21)13(23)17(2)8(7)5-10-19-6-28-18(3,14(24)11(22)12(17)19)20(19,27)15(25)16(26)29-10/h4,8,10-15,22-25,27H,5-6H2,1-3H3/t8-,10+,11+,12+,13-,14-,15-,17-,18+,19+,20+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The seeds of Brucea javanica.
| Description | 1. Yadanziolide C induces differentiation with cultured HL-60 promyelocytic leukemia cells. |
Yadanziolide C Dilution Calculator
Yadanziolide C Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.4366 mL | 12.1829 mL | 24.3659 mL | 48.7318 mL | 60.9147 mL |
| 5 mM | 0.4873 mL | 2.4366 mL | 4.8732 mL | 9.7464 mL | 12.1829 mL |
| 10 mM | 0.2437 mL | 1.2183 mL | 2.4366 mL | 4.8732 mL | 6.0915 mL |
| 50 mM | 0.0487 mL | 0.2437 mL | 0.4873 mL | 0.9746 mL | 1.2183 mL |
| 100 mM | 0.0244 mL | 0.1218 mL | 0.2437 mL | 0.4873 mL | 0.6091 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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A lignan and four terpenoids from Brucea javanica that induce differentiation with cultured HL-60 promyelocytic leukemia cells.[Pubmed:8862033]
Phytochemistry. 1996 Sep;43(2):409-12.
A novel lignan, guaiacylglycerol-beta-O-6'-(2-methoxy)cinnamyl alcohol either, three known simaroubolides, brusatol, dehydrobrusatol, Yadanziolide C, and the known terpenoid, blumenol A, were obtained as active compounds from an ethyl acetate-soluble extract of Brucea javanica, using a bioassay based on the induction of cell differentiation with human promyelocytic leukemia (HL-60) cells. Also obtained were the known coumarinolignan, cleomiscosin A, and the known quassinoid glycoside, bruceoside B, which were inactive in the HL-60 cell test system. The structure of the new lignan was determined by a combination of 1D and 2D NMR techniques.
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