Cancer Research

Cancer is a term used to define a group of diseases in which abnormal cells divide without control, are able to invade neighboring tissues/organs and metastasize. Cancer has been characterized by six hallmarks; self sufficiency in proliferative growth signals, insensitivity to growth inhibitors, evasion of apoptosis, limitless replicative potential, ability to develop blood vessels (angiogenesis), and tissue invasion and metastasis.

Cancer Research Products Areas

Products for Cancer Research - Page 106

Cat.No. Product Name Information/Activity
BCC3631 PP 2 (AG 1879) PP2 is a reversible and ATP-competitive Src family kinases inhibitor with IC50s of 4 and 5 nM for Lck and Fyn, respectively.
BCC5851 pp60 c-src (521-533) (phosphorylated) 149299-77-4
BCC7733 Src I1 Src Inhibitor 1 is a potent and selective dual site Src tyrosine kinase inhibitor with IC50 values of 44 nM for Src and 88nM for Lck.
BCC1689 Lck Inhibitor Lck Inhibitor is a new class of compounds that are potent inhibitors of Lck with an IC50 value of 7 nM.
BCC8051 WH-4-023 WH-4-023 is a potent and selective dual Lck/Src inhibitor with IC50 of 2 nM/6 nM for Lck and Src kinase respectively; little inhibition on p38α and KDR.
BCC6232 MLR 1023 Tolimidone is a potent and selective allosteric activator of Lyn kinase with an EC50 of 63 nM.
BCC5855 N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide 190078-50-3
BCC5853 N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu 159439-02-8
BCC3799 Nilvadipine Nilvadipine is a potent calcium channel antagonist, and the IC50 value is around 0.1 nM.
BCC8085 c-JUN peptide 610273-01-3