Cancer Research
Cancer is a term used to define a group of diseases in which abnormal cells divide without control, are able to invade neighboring tissues/organs and metastasize. Cancer has been characterized by six hallmarks; self sufficiency in proliferative growth signals, insensitivity to growth inhibitors, evasion of apoptosis, limitless replicative potential, ability to develop blood vessels (angiogenesis), and tissue invasion and metastasis.
Cancer Research Products Areas
Products for Cancer Research - Page 110
- Cat.No. Product Name Information/Activity
-
BCC6166
SR 1664
1338259-05-4
-
BCC6199
Cardionogen 1
577696-37-8
-
BCC6258
CCT 031374 hydrobromide
1219184-91-4
-
BCC3632
ICG 001
ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to CREB-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.
-
BCC5401
iCRT 14
iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT), with IC50 of 40.3 nM against Wnt responsive STF16 luciferase.
-
BCC5602
IWP 4
IWP-4 is a small molecule Wnt inhibitor with an IC50 of 25 nM.
-
BCC5102
IWR-1-endo
IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway.
-
BCC7823
exo-IWR 1
1127442-87-8
-
BCC6251
JW 67
442644-28-2
-
BCC7704
PNU 74654
PNU-74654 is an inhibitor of Wnt/β-catenin pathway with an IC50 of 129.8 μM in NCI-H295 cell.


