Cancer Research

Cancer is a term used to define a group of diseases in which abnormal cells divide without control, are able to invade neighboring tissues/organs and metastasize. Cancer has been characterized by six hallmarks; self sufficiency in proliferative growth signals, insensitivity to growth inhibitors, evasion of apoptosis, limitless replicative potential, ability to develop blood vessels (angiogenesis), and tissue invasion and metastasis.

Cancer Research Products Areas

Products for Cancer Research - Page 110

  1. Cat.No. Product Name Information/Activity
  2. BCC6166 SR 1664 1338259-05-4 SR 1664 chemical structure
  3. BCC6199 Cardionogen 1 577696-37-8 Cardionogen 1 chemical structure
  4. BCC6258 CCT 031374 hydrobromide 1219184-91-4 CCT 031374 hydrobromide chemical structure
  5. BCC3632 ICG 001 ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to CREB-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300. ICG 001 chemical structure
  6. BCC5401 iCRT 14 iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT), with IC50 of 40.3 nM against Wnt responsive STF16 luciferase. iCRT 14 chemical structure
  7. BCC5602 IWP 4 IWP-4 is a small molecule Wnt inhibitor with an IC50 of 25 nM. IWP 4 chemical structure
  8. BCC5102 IWR-1-endo IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway. IWR-1-endo chemical structure
  9. BCC7823 exo-IWR 1 1127442-87-8 exo-IWR 1 chemical structure
  10. BCC6251 JW 67 442644-28-2 JW 67 chemical structure
  11. BCC7704 PNU 74654 PNU-74654 is an inhibitor of Wnt/β-catenin pathway with an IC50 of 129.8 μM in NCI-H295 cell. PNU 74654 chemical structure

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