PPARδ
Peroxisome proliferator-activated receptor delta (PPARδ ), also known as PPARβ , is a member of the nuclear receptor family of ligand-activated transcription factors that heterodimerize with the retinoic X receptor (RXR) to regulate gene expression.
Products for PPARδ
- Cat.No. Product Name Information/Activity
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BCC2267
GW0742
GW0742 is a potent PPARβ and PPARδ agonist, with an IC50 of 1 nM for human PPARδ in binding assay, and EC50s of 1 nM, 1.1 μM and 2 μM for human PPARδ, PPARα, and PPARγ, respectively.
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BCC2268
GW501516
GW 501516 is a PPARδ agonist with an EC50 of 1.1 nM.
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BCC1573
FH535
FH535 is an inhibitor of Wnt/β-catenin and PPAR, with anti-tumor activities.
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BCC7688
GSK 0660
GSK0660 is a potent antagonist of PPARβ and PPARδ, with IC50s of 155 nM for both isoforms.
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BCC2263
GSK3787
GSK3787 is as a selective and irreversible antagonist of PPARδ with pIC50 of 6.6, with no measurable affinity for hPPARα or hPPARγ.
