Cardiovascular System Research
The cardiovascular, or circulatory, system is a closed elastic circuit consisting of the heart, blood vessels (arteries, capillaries and veins) and the blood. The primary function is to pump oxygenated blood to the tissues throughout the body and reabsorb waste carbon dioxide for its removal. This function is performed by the use of pulmonary and systemic circulation.
Cardiovascular System Research Products Areas
Products for Cardiovascular System Research - Page 53
- Cat.No. Product Name Information/Activity
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BCC3797
Isradipine (Dynacirc)
Isradipine(Dynacirc) is a calcium channel blocker with an IC50 of 34±8 μM.
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BCC7561
L-651,582
Carboxyamidotriazole (L-651582) is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole shows anti-tumor, anti-inflammatory and antiangiogenic effects.
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BCC5238
Lercanidipine hydrochloride
Lercanidipine hydrochloride is a calcium channel blocker of the dihydropyridine class.
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BCC4380
Loperamide HCl
Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist. Loperamide hydrochloride is a selective and competitive
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BCC1749
Mibefradil dihydrochloride
Mibefradil dihydrochloride (Ro 40-5967 dihydrochloride) is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively.
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BCC4808
Nifedipine
Nifedipine (BAY-a-1040) is a potent calcium channel blocker and drug of choice for cardiac insufficiencies.
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BCC3799
Nilvadipine
Nilvadipine is a potent calcium channel antagonist, and the IC50 value is around 0.1 nM.
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BCC3823
Nimodipine
Nimodipine(Nimotop) is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.
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BCC4381
Nitrendipine
Nitrendipine is a calcium channel blocker with marked vasodilator action.
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BCC1803
NNC 55-0396
NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and > 100 μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells.


