Endocrinology Research
Endocrinology is the study of hormones, their signaling pathways, and the diseases associated with them. The endocrine system is one of two mechanisms in the human body that is responsible for regulating and integrating the function of cells, the other being the nervous system.
Endocrinology Research Products Areas
Products for Endocrinology Research - Page 17
- Cat.No. Product Name Information/Activity
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BCC7613
BMS 193885
Potent, competitive NPY Y<sub>1</sub> receptor antagonist
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BCC5882
BVD 10
Highly selective NPY Y<sub>1</sub> receptor antagonist; devoid of Y<sub>4</sub> agonist activity
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BCC7283
CGP 71683 hydrochloride
CGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a Ki of 1.3 nM, and shows no obvious activity at Y1 receptor (Ki, >4000 nM) and Y2 receptor (Ki, 200 nM) in cell membranes.
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BCC6238
CYM 9484
CYM 9484 is a selective and highly potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM.
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BCC6100
JNJ 5207787
JNJ-5207787 is a nonpeptidic, selective and penetrate the blood-brain barrier neuropeptide Y Y2 receptor (Y2) antagonist. JNJ-5207787 inhibits the binding of peptide YY (PYY) with pIC50s of 7.0 and 7.1 for human Y2 receptor and rat Y2 receptor, respectively. JNJ-5207787 is >100-fold selective versus human Y1, Y4, and Y5 receptors.
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BCC7041
L-152,804
L 152804 is an orally active and selective neuropeptide Y Y5 receptor (NPY5-R) antagonist, with a Ki of 26 nM for hY5. L 152804 causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure.
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BCC7708
LU AA33810
304008-29-5
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BCC7747
NPY 5RA972
439861-56-0
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BCC7270
NTNCB hydrochloride
191931-56-3
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BCC7284
PD 160170
181468-88-2
