NK2 Receptor

The neurokinin 2 (NK2) receptor is a member of the tachykinin family of G-protein-coupled receptors which also includes NK1 and NK3 receptors. The NK2 receptor is predominantly expressed in the periphery (including inflammatory cells and bronchial smooth muscle).

Products for NK2 Receptor

Cat.No. Product Name Information/Activity
BCC5800 GR 64349 137593-52-3
BCC7137 [bAla8]-Neurokinin A(4-10) [bAla8]-Neurokinin A(4-10) is a neurokinin 2 (NK2) receptor agonist.
BCC5994 [Lys5,MeLeu9,Nle10]-NKA(4-10) 137565-28-7
BCC7001 GR 159897 GR 159897 is a highly potent, selective, competitive, brain-penetrated non-peptide neurokinin 2 (NK2) receptor antagonist. GR 159897 has little or no affinity for NK1 and NK3 receptors. GR 159897 inhibits binding of [3H]GR100679 to human NK2 (hNK2)-CHO cells and rat colon membranes with pKis of 9.51 and 10, respectively. Antagonizes bronchoconstriction. Anxiolytic-like and anti-tumor effects.
BCC5799 GR 94800 141636-65-9
BCC5729 MDL 29,913 135721-56-1
BCC7133 MEN 10376 Men 10376 is a selective tachykinin NK-2 receptor antagonist, with a Ki of 4.4 μM for rat small intestine NK-2 receptor.