Sigma1 Receptor

σ 1 receptors are members of the σ family of receptors that also includes σ 2 receptors. They are distinguished from σ 2 receptors as they have high affinity and stereoselectivity for the (+)-isomers of pentazocine, SK&F 10047 and cyclazocine, and different subcellular localizations.

Products for Sigma1 Receptor

Cat.No. Product Name Information/Activity
BCC7796 (±)-PPCC oxalate 932736-91-9
BCC6339 SA 4503 dihydrochloride Cutamesine dihydrochloride (SA4503 dihydrochloride; AGY94806 dihydrochloride) is a potent Sigma 1 receptor agonist with an IC50 of 17.4 nM in guinea pig brain membranes.
BCC6928 (+)-SK&F 10047 hydrochloride 133005-41-1
BCC6863 BD 1047 dihydrobromide BD-1047 (dihydrobromide) is a selective functional antagonist of sigma-1 receptor, shows antipsychotic activity in animal models predictive of efficacy in schizophrenia.
BCC7573 NE 100 hydrochloride 149409-57-4
BCC6832 BD 1063 dihydrochloride BD1063 dhydrochloride is a potent and selective sigma 1 receptor antagonist.
BCC4697 Pentoxyverine Citrate Pentoxyverine Citrate is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold.
BCC7280 Eliprodil Eliprodil(SL-820715) is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM).
BCC1215 Fluvoxamine maleate Fluvoxamine maleate (DU-23000 maleate) is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor.
BCC4251 Haloperidol hydrochloride Haloperidol hydrochloride is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic.