Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research

  1. Cat.No. Product Name Information/Activity
  2. BCC7995 2-MPPA 254737-29-6 2-MPPA chemical structure
  3. BCC6587 cis-ACBD 73550-55-7 cis-ACBD chemical structure
  4. BCC6608 L-CCG-lll 117857-95-1 L-CCG-lll chemical structure
  5. BCC6816 Chicago Sky Blue 6B 2610-05-1 Chicago Sky Blue 6B chemical structure
  6. BCC7757 7-Chlorokynurenic acid sodium salt 7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery. 7-Chlorokynurenic acid sodium salt chemical structure
  7. BCC6577 7-Chlorokynurenic acid 7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery. 7-Chlorokynurenic acid chemical structure
  8. BCC6556 Dihydrokainic acid 52497-36-6 Dihydrokainic acid chemical structure
  9. BCC6815 Evans Blue tetrasodium salt Selective P2X purinergic antagonist,Evans Blue is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Evans Blue tetrasodium salt chemical structure
  10. BCC7295 (±)-HIP-B 227619-65-0 (±)-HIP-B chemical structure
  11. BCC6565 L-(-)-threo-3-Hydroxyaspartic acid 7298-99-9 L-(-)-threo-3-Hydroxyaspartic acid chemical structure

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