Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research - Page 71

  1. Cat.No. Product Name Information/Activity
  2. BCC4251 Haloperidol hydrochloride Haloperidol hydrochloride is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic. Haloperidol hydrochloride chemical structure
  3. BCC6777 4-IBP 4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) . 4-IBP chemical structure
  4. BCC5902 (+)-Igmesine hydrochloride 130152-35-1 (+)-Igmesine hydrochloride chemical structure
  5. BCC7429 PD 144418 oxalate PD 144418 is a highly affinity, potent and selective sigma 1 (σ1) receptor ligand (Ki values of 0.08 nM and 1377 nM for σ1 and σ2 respectively), devoid of any significant affinity for other receptors, ion channels and enzymes. PD 144418 shows potential antipsychotic activity. PD 144418 oxalate chemical structure
  6. BCC6784 N-[2-(Piperidinylamino)ethyl]-4-iodobenzamide 155054-42-5 N-[2-(Piperidinylamino)ethyl]-4-iodobenzamide chemical structure
  7. BCC7450 TC 1 362512-81-0 TC 1 chemical structure
  8. BCC7411 PB 28 dihydrochloride 172907-03-8 PB 28 dihydrochloride chemical structure
  9. BCC7090 Rimcazole dihydrochloride 75859-03-9 Rimcazole dihydrochloride chemical structure
  10. BCC6780 SM-21 maleate 155059-42-0 SM-21 maleate chemical structure

Items 701 to 709 of 709 total