Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research - Page 59

  1. Cat.No. Product Name Information/Activity
  2. BCC7619 Ro 61-8048 Ro 61-8048 is a potent and selective inhibitors of kynurenine hydroxylase with IC50 of 37 nM. Ro 61-8048 chemical structure
  3. BCC7655 Ro 8-4304 hydrochloride 1312991-77-7 Ro 8-4304 hydrochloride chemical structure
  4. BCC6992 SDZ 220-040 174575-40-7 SDZ 220-040 chemical structure
  5. BCC1939 SDZ 220-581 SDZ 220-581 is an orally active, potent, competitive NMDA receptor antagonist with pKi value of 7.7. SDZ 220-581 chemical structure
  6. BCC6730 Synthalin sulfate 182285-12-7 Synthalin sulfate chemical structure
  7. BCC6122 TCN 201 852918-02-6 TCN 201 chemical structure
  8. BCC6123 TCN 213 556803-08-8 TCN 213 chemical structure
  9. BCC6111 TCN 237 dihydrochloride NMDA-IN-1 is a potent and NR2B-selective NMDA antagonist with Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM; no activities on NR2A, NR2C, NR2D, hERG-channel and α1-adrenergic receptor. TCN 237 dihydrochloride chemical structure
  10. BCC7482 TCS 46b 302799-86-6 TCS 46b chemical structure
  11. BCC6984 CCMQ 132623-44-0 CCMQ chemical structure

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