Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research - Page 52

Cat.No. Product Name Information/Activity
BCC5051 Lamotrigine Lamotrigine(BW430C) is a novel anticonvulsant drug for inhibition of 5-HT and sodium channel Target: Sodium Channel Lamotrigine stabilises presynaptic neuronal membranes by blockade of voltage-dependent sodium channels, thus preventing the release of excitatory neurotransmitters, particularly glutamate and aspartate [1].
BCC7086 MNI-caged-L-glutamate 295325-62-1
BCC7453 Pentylenetetrazole 54-95-5
BCC6731 Salsolinol-1-carboxylic acid 57256-34-5
BCC6632 Spaglumic acid Spaglumic Acid is a neuropeptide found in millimolar concentrations in brain.
BCN2571 L-Theanine L-Theanine (L-Glutamic Acid γ-ethyl amide）is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. L-Theanine causes anti-stress effects via the inhibition of cortical neuron excitation by oral intake.
BCC2512 Zonisamide Zonisamide is a 1,2 benzisoxazole derivative and the first agent of this chemical class to be developed as an antiepileptic drug.
BCC6566 cis-ACPD 477331-06-9
BCC2894 H-D-Asp-OH (-)-Aspartic acid is an endogenous NMDA receptor agonist.
BCC2881 H-Asp-OH L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly.