Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research - Page 58

  1. Cat.No. Product Name Information/Activity
  2. BCC5859 Norketamine hydrochloride 79499-59-5 Norketamine hydrochloride chemical structure
  3. BCC7895 NPEC-caged-D-AP5 1416943-27-5 NPEC-caged-D-AP5 chemical structure
  4. BCC5644 Pentamidine isethionate Pentamidine isethionate (MP-601205 isethionate) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine isethionate inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine isethionate is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine isethionate has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities. Pentamidine isethionate chemical structure
  5. BCC7308 PMPA (NMDA antagonist) 113919-36-1 PMPA (NMDA antagonist) chemical structure
  6. BCC5918 PPDA 684283-16-7 PPDA chemical structure
  7. BCC7309 PPPA 113190-92-4 PPPA chemical structure
  8. BCC6292 QNZ 46 QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist (IC50 values are 3, 6, 229, and >300, >300 μM for NR2D, NR2C, NR2A, NR2B, and GluR1, respectively). QNZ 46 chemical structure
  9. BCC7129 Remacemide hydrochloride 111686-79-4 Remacemide hydrochloride chemical structure
  10. BCC7234 Ro 04-5595 hydrochloride 64047-73-0 Ro 04-5595 hydrochloride chemical structure
  11. BCC4159 Ro 25-6981 Maleate Ro 25-6981 Maleate is a potent and selective activity-dependent blocker of NMDA receptors containing the NR2B subunit. Ro 25-6981 Maleate chemical structure

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