Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research - Page 6

  1. Cat.No. Product Name Information/Activity
  2. BCN2166 Rasagiline mesylate Rasagiline mesylate is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease. Rasagiline mesylate chemical structure
  3. BCC6763 Tetrindole mesylate 170964-68-8 Tetrindole mesylate chemical structure
  4. BCC7791 Tranylcypromine hydrochloride Tranylcypromine is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively. Tranylcypromine hydrochloride chemical structure
  5. BCC5863 JMV 449 139026-66-7 JMV 449 chemical structure
  6. BCC5845 Kinetensin (human) Kinetensin is a neurotensin-like peptide isolated from pepsin-treated human plasma. Kinetensin (human) chemical structure
  7. BCC5840 Neuromedin N (rat, mouse, porcine, canine) Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Neuromedin N (rat, mouse, porcine, canine) chemical structure
  8. BCC5842 Neurotensin Neurotensin, a gut tridecapeptide, acts as a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinity neurotensin receptors (NTR). Neurotensin chemical structure
  9. BCC5876 Xenin 8 117442-28-1 Xenin 8 chemical structure
  10. BCC7323 SR 142948 184162-64-9 SR 142948 chemical structure
  11. BCC7763 SR 48692 Meclinertant (SR 48692) is a potent, selective, nonpeptide and orally active neurotensin receptor 1 (NTS1) antagonist. In human colon carcinoma (HT-29) cells, Meclinertant competitively antagonizes neurotensin-induced intracellular Ca2+ mobilization with a pA2 values of 8.13. Meclinertant has anxiolytic, anti-addictive and memory-impairing effects. SR 48692 chemical structure

Items 51 to 60 of 709 total