Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research - Page 4

  1. Cat.No. Product Name Information/Activity
  2. BCC6781 Clobenpropit dihydrobromide Clobenpropit dihydrobromide is a potent histamine H3R antagonist/inverse agonist with a pEC50 of 8.07 for histamine H3LR. Clobenpropit dihydrobromide acts as partial agonist at histamine H4 receptors (Ki 13 nM). Clobenpropit dihydrobromide also binds to serotonin 5-HT3 receptors (Ki 7.4 nM) and α2A/α2C adrenoceptors (Ki 17.4/7.8 nM). Clobenpropit dihydrobromide increases apoptosis. Clobenpropit dihydrobromide chemical structure
  3. BCC7352 Conessine 546-06-5 Conessine chemical structure
  4. BCC7357 GT 2016 152241-24-2 GT 2016 chemical structure
  5. BCC7197 Impentamine dihydrobromide 149629-70-9 Impentamine dihydrobromide chemical structure
  6. BCC6793 Iodophenpropit dihydrobromide Iodophenpropit dihydrobromide is a potent and selective histamine H3 receptor antagonist. The binding of [125I]Iodophenpropit is selective, saturable, readily reversible, and of high affinity (KD 0.32 nM). Iodophenpropit dihydrobromide chemical structure
  7. BCC7842 JNJ 10181457 dihydrochloride 544707-20-2 JNJ 10181457 dihydrochloride chemical structure
  8. BCC6101 JNJ 5207852 dihydrochloride JNJ-5207852 is a selective and potent histamine H3 receptor (H3R) antagonist, with pKis of 8.9, 9.24 for rat and human H3R, respectively. JNJ 5207852 dihydrochloride chemical structure
  9. BCC7245 ROS 234 dioxalate 184576-87-2 ROS 234 dioxalate chemical structure
  10. BCC6182 SEN 12333 874450-44-9 SEN 12333 chemical structure
  11. BCC6734 Thioperamide 106243-16-7 Thioperamide chemical structure

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