Pain and Inflammation Research

Although separate conditions, pain and inflammation are nearly always associated with each other. Pain is defined by the International Association for the Study of Pain (IASP) as 'an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage'. Inflammation is the tissue's immunologic response to injury, characterized by mobilization of white blood cells and antibodies, swelling, and fluid accumulation.

Pain and Inflammation Research Products Areas

Products for Pain and Inflammation Research - Page 109

Cat.No. Product Name Information/Activity
BCC6922 Zolantidine dimaleate 104076-39-3
BCC6768 Imetit dihydrobromide Imetit dihydrobromide (VUF 8325 dihydrobromide) is a high affinity and potent agonist of histamine H3 and H4 receptors, with Ki values of 0.3 and 2.7 nM, respectively. Imetit mimics histamine effect in triggering a shape change in eosinophils (EC50=25 nM).
BCC6853 Immepip dihydrobromide 164391-47-3
BCC7524 Methimepip dihydrobromide 817636-54-7
BCC5665 (R)-(-)-α-Methylhistamine dihydrobromide (R)-(-)-α-Methylhistamine dihydrobromide is a potent and selective H3 histamine receptor agonist with a Kd of 50.3 nM. (R)-(-)-α-Methylhistamine dihydrobromide can cross the blood-brain barrier, and can enhance memory retention, attenuates memory impairment in rats.
BCC6700 (S)-(+)-α-Methylhistamine dihydrobromide 75614-93-6
BCC6701 Nα-Methylhistamine dihydrochloride 16503-22-3
BCC7378 Proxyfan oxalate 177708-09-7
BCC7963 A 331440 dihydrochloride Selective H<sub>3</sub> antagonist
BCC1863 Pitolisant hydrochloride Pitolisant hydrochloride is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor (Ki=0.16 nM).