Asthma Research
Asthma is a common chronic inflammatory disease of the respiratory system that affects approximately 22 million people in US. It has been classified as a complex genetic condition that is determined by the interaction of numerous genes along with environmental factors.
Asthma Research Products Targets
- Adenosine A2B Receptor (7)
- Adenosine A2A Receptor (11)
- Matrix Metalloprotease (16)
- Caspase (10)
- Elastase (1)
- Lipoxygenase (8)
- Leukotriene and Related Receptor (13)
- Bradykinin Receptor (12)
- Cytokine Receptor (4)
- Urokinase (2)
- Deubiquitinating Enzyme (12)
- Aminopeptidase (5)
- Angiotensin-Converting Enzyme (8)
- Carboxypeptidase (1)
- Calpain (7)
- Histamine H4 Receptor (12)
- Histamine H3 Receptor (22)
- Histamine H2 Receptor (10)
- Histamine H1 Receptor (17)
- Adenosine A3 Receptor (8)
- Adenosine A1 Receptor (12)
- IαB Kinase (6)
- Calcium-Activated Potassium (KCa) Channel (19)
- Dipeptidyl Peptidase IV (1)
- Cathepsin (9)
- gamma-Secretase (9)
- ADAMs (1)
- Proteasome (5)
Products for Asthma Research - Page 15
- Cat.No. Product Name Information/Activity
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BCC6734
Thioperamide
106243-16-7
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BCC7383
VUF 5681 dihydrobromide
639089-06-8
-
BCC7337
4-Methylhistamine dihydrochloride
Selective, high affinity H<sub>4</sub> agonist
-
BCC6285
VUF 10460
VUF10460 is a non-imidazole histamine H4 receptor agonist; binds to rat H4 receptor with a pKi of 7.46.
-
BCC7384
VUF 8430 dihydrobromide
100130-32-3
-
BCC7772
A 943931 dihydrochloride
Potent and selective H<sub>4</sub> antagonist
-
BCC7732
A 987306
Potent and selective H<sub>4</sub> receptor antagonist
-
BCC7362
JNJ 10191584 maleate
869497-75-6
-
BCC4543
JNJ-7777120
JNJ-7777120 is a selective H4R antagonist with Ki of 4 ±1 nM, exhibits >1000-fold selectivity over the other histamin receptors.
-
BCC2374
GI 254023X
GI254023X is a potent MMP9 and ADAM10 inhibitor with IC50s of 2.5 and 5.3 nM, respectively.
