Others Products Targets
- Adenosine A2B Receptor (7)
- Adenosine A2A Receptor (11)
- Matrix Metalloprotease (16)
- LXR-like Receptor (6)
- Elastase (1)
- EGFR (28)
- Voltage-gated Sodium (NaV) Channel (30)
- Lipoxygenase (8)
- Leukotriene and Related Receptor (13)
- Others (6)
- Glucocorticoid Receptor (9)
- Cytokine Receptor (4)
- Cyclooxygenase (24)
- Vitamin D Receptor (10)
- Progesterone Receptor (4)
- Mineralocorticoid Receptor (7)
- Pregnane X Receptor (3)
- Constitutive Androstane Receptor (5)
- Aryl Hydrocarbon Receptor (8)
- 5-HT7 Receptor (11)
- 5-HT6 Receptor (14)
- 5-ht5 Receptor (2)
- 5-HT4 Receptor (17)
- GPR55 (8)
- CB2 Receptor (6)
- CB1 Receptor (17)
- Retinoic Acid-related Orphan Receptor (4)
- Rev-Erb Receptor (2)
- Estrogen and Related Receptor (33)
- Histamine H4 Receptor (12)
- Histamine H3 Receptor (22)
- Histamine H2 Receptor (10)
- Histamine H1 Receptor (17)
- Chemokine CXC Receptor (9)
- Chemokine CC Receptor (13)
- Adenosine A3 Receptor (8)
- Adenosine A1 Receptor (12)
- Calcitonin and Related Receptor (10)
- Androgen Receptor (11)
- Adrenergic α2 Receptor (33)
- Adrenergic α1 Receptor (22)
- Adrenergic β3 Receptor (12)
- Adrenergic β2 Receptor (6)
- Adrenergic β1 Receptor (7)
- Protease-Activated Receptor (23)
- Retinoid X Receptor (13)
- Retinoic Acid Receptor (22)
- Prostanoid Receptor (24)
- Sphingosine-1-Phosphate Receptor (13)
- Platelet-Activating Factor (PAF) Receptor (5)
- Phosphodiesterase (34)
Products for Others - Page 59
- Cat.No. Product Name Information/Activity
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BCC6321
CYM 5541
CYM-5541 (ML249) is an selective and allosteric S1P3 receptor agonist with an EC50 between 72 and 132 nM.
-
BCC7905
RP 001 hydrochloride
RP-001 is a picomolar short-acting S1P1 (EDG1) selective agonist, with an EC50 of 9 pM. RP-00 induces internalization and polyubiquitination of S1P1. RP-001 has little activity on S1P2-S1P4 and only moderate affinity for S1P5.
-
BCC7312
SEW 2871
SEW2871 is a highly selective, orally active S1P1 agonist with an EC50 of 13.8 nM. SEW2871 activates ERK, Akt, and Rac signaling pathways and induces S1P1 internalization and recycling. SEW2871 reduces lymphocyte numbers in blood and has therapeutic implications in contexts of diabetes, Alzheimer’s disease, liver fibrosis, and inflammatory responses.
-
BCC7034
Sphingosine-1-phosphate
Endogenous agonist at S1P<sub>1-5</sub>
-
BCC6277
TC-G 1006
S1P1 Agonist III is a potent and orally active S1P1 agonist with EC50 of 18 nM; no activity on S1P3.
-
BCC7926
TC-SP 14
Potent S1P<sub>1</sub> receptor agonist
-
BCC7348
JTE 013
547756-93-4
-
BCC7883
VPC 23019
VPC 23019, an aryl amide-containing Sphingosine 1-phosphate (S1P) analog, is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively) and an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively).
-
BCC7723
W146
W146 is a selective antagonist of sphingosine-1-phosphate receptor 1 (S1PR1) with an EC50 value of 398 nM.
-
BCC7515
Veratridine
Veratridine (3-Veratroylveracevine), a alkaloid derived from plants in the family Liliaceae, is a sodium channel agonist. Veratridine inhibits the peak current of Nav1.7, with an IC50 of 18.39 µM.
