Protease-Activated Receptor
Protease-activated receptors (PARs, also known as thrombin receptors) are G-protein-coupled receptors, activated by cleavage of their N-terminal domains by serine proteases. Hydrolysis reveals a tethered peptide ligand, which affects transmembrane signaling.
Products for Protease-Activated Receptor
- Cat.No. Product Name Information/Activity
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BCC3952
AC 264613
PAR<sub>2</sub> receptor agonist
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BCC3951
AC 55541
AC-55541 is a highly selective protease-activated receptor 2 (PAR2) agonist (pEC50=6.7), displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. AC-55541 has pEC50 values of 5.9 and 6.6 in PI hydrolysis assays and Ca2+ mobilization assays and exhibits pronociceptive activity in vivo.
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BCC3949
AY-NH2
PAR-4 Agonist Peptide, amide (PAR-4-AP; AY-NH2) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist.
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BCC3958
2-Furoyl-LIGRLO-amide
2-Furoyl-LIGRLO-amide is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0..
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BCC3955
LRGILS-NH2
245329-01-5
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BCC3954
RLLFT-NH2
447408-68-6
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BCC3959
SLIGKV-NH2
Protease-Activated Receptor-2, amide (SLIGKV-NH2) is a highly potent protease-activated receptor-2 (PAR2) activating peptide.
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BCC3947
SLIGRL-NH2
Protease-Activated Receptor-2 Activating Peptide is an agonist of Protease-Activated Receptor-2 (PAR-2).
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BCC3948
TFLLR-NH2
TFLLR-NH2 is a selective PAR1 agonist with an EC50 of 1.9 μM.
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BCC3950
Thrombin Receptor Agonist Peptide
Sfllrnpndkyepf is a synthetic thrombin receptor agonist peptide.
