Protease-Activated Receptor
Protease-activated receptors (PARs, also known as thrombin receptors) are G-protein-coupled receptors, activated by cleavage of their N-terminal domains by serine proteases. Hydrolysis reveals a tethered peptide ligand, which affects transmembrane signaling.
Products for Protease-Activated Receptor - Page 3
- Cat.No. Product Name Information/Activity
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BCC3642
ML161
Parmodulin 2 (ML161) is an allosteric inhibitor of protease-activated receptor 1 (PAR1) with an IC50 of 0.26 μM. Parmodulin 2 is a potent and non-competitive inhibitor of SFLLRN-induced P-selectin expression leading to inhibition of platelet aggregation in vitro and platelet thrombus formation in vivo.
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BCC6041
Parstatin (human)
1065755-99-8
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BCC6042
Parstatin (mouse)
1065756-01-5
