Aryl Hydrocarbon Receptor
Aryl hydrocarbon receptors (AHRs) are cytosolic transcription factors that exist bound to co-chaperones in the resting state. Ligand binding causes the co-chaperones to dissociate, allowing AHR to translocate to the nucleus, dimerize and alter transcription of target genes.
Products for Aryl Hydrocarbon Receptor
- Cat.No. Product Name Information/Activity
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BCC5513
FICZ
FICZ is a potent aryl hydrocarbon receptor (AhR) agonist with a Kd of 70 pM.
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BCC3898
MeBIO
667463-95-8
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BCC2241
Pifithrin-α (PFTα)
Pifithrin-α hydrobromide is a p53 inhibitor which blocks its transcriptional activity and prevents cells from apoptosis. Pifithrin-α hydrobromide is also an aryl hydrocarbon receptor (AhR) agonist.
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BCC3896
CH 223191
CH-223191 is a potent and specific antagonist of aryl hydrocarbon receptor (AhR). CH-223191 inhibits TCDD-mediated nuclear translocation and DNA binding of AhR, and inhibits TCDD-induced luciferase activity with an IC50 of 0.03 μM.
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BCC3897
6,2',4'-Trimethoxyflavone
720675-74-1
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BCC3900
DiMNF
Selective aryl hydrocarbon receptor modulator (SAhRM)
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BCC3899
L-Kynurenine
L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.
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BCC3901
Phortress
Prodrug of the antitumor agent 5F 203
