P450
Cytochrome P450 are a family of heme-containing monoxygenases catalyzing the metabolism of xenobiotics in the body where P450 enzymes use O2 and two electrons provided by NAD(P)H with the help of redox partner flavoproteins and iron-sulfur proteins to catalyze the monooxygenation of a variety of substrates. Based on how electrons from NAD(P)H are delivered to the catalytic site, P450 enzymes are divided into four classes, including Class I requiring both an FAD-containing reductase and an iron sulfur redoxin, Class II requiring only an FAD/FMN-containg P450 reductase, Class III requiring no electron donor and Class IV requiring electrons directly from NAD(P)H.
Products for P450
- Cat.No. Product Name Information
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BCN2184
Abiraterone Acotate
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BCN3479
Alizarin
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BCC2259
AbirateronePotent CYP17 inhibitor
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BCC2270
PF-4981517Selective CYP3A4 inhibitor
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BCC2272
KetoconazoleCytochrome P450c17 inhibitor
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BCC2274
AvasimibeACAT inhibitor,orally bioavailable
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BCC4249
(+)-Ketoconazole