Substance P/NK1 Receptor - Neuroscience

Cat.No. Product Name Information

BCC6960 [Sar9,Met(O2)11]-Substance P [Sar9,Met(O2)11]-Substance P is a tachykinin NK1 receptor selective agonist.

BCC5802 GR 82334

BCC7509 CP 96345

BCC5801 GR 73632 GR-73632 is a novel tachykinin neurokinin 1 (NK-1) receptor agonist. GR-73632 acts directly on the peripheral terminals of primary sensory neurons through NK1 receptor which convey itch signals.

BCC7134 RP 67580

BCC5907 FK 888 FK 888

BCC4154 ML314 ML314 is a potent molecule agonist of NTR1 (EC50 = 1.9 μM); showed good selectivity against NTR2 and GPR35, but did not stimulate Ca2+ mobilization. ML314

BCC6016 CP 99994 dihydrochloride

BCC1728 Maropitant Maropitant is a neurokinin (NK1) receptor antagonist.

BCC6821 L-732,138 L-732138 is a selective, potent and competitive neurokinin-1 (NK-1) receptor antagonist with an IC50 of 2.3 nM. L-732138 has 200-fold more potent in cloned human NK-1 receptors than cloned rat NK-1 receptors, and has > 1000-fold more potent than human NK-2 and NK-3 receptors. L-732138 can reduce hyperalgesia and has antitumor action. L-732,138

BCC5707 L-733,060 hydrochloride

BCC6098 SR 140333

BCC1101 Aprepitant Aprepitant (MK-0869) is a selective and high-affinity neurokinin 1 receptor antagonist with a Kd of 86 pM.

BCC4281 Fosaprepitant Fosaprepitant (L-758298) is a neurokinin-1 receptor antagonist for the prevention of chemotherapy-induced nausea and vomiting.

BCC1802 NKP608 NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo. NKP608

BCC7349 SDZ NKT 343

BCC7840 L 760735

BCC5774 Hemokinin 1 (mouse) Hemokinin 1 (mouse) is a selective agonist of neurokinin-1 receptor, with Ki of 0.175 nM and 560 nM for human NK1 receptor and human NK2 receptor, respectively.

BCC4954 Fosaprepitant dimeglumine salt Fosaprepitant dimeglumine(MK-0517) is a neurokinin-1 receptor antagonist for the prevention of chemotherapy-induced nausea and vomiting.

BCC5923 Hemokinin 1 (human)

BCC5808 Spantide I

Products for Substance P/NK1 Receptor