Products with Analgesia bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3341 | alpha-Amyrin |
| 1. Alpha-Amyrin is an antineoplastic agent. 2. Alpha-Amyrin is trypsin and chymotrypsin inhibitor. 3. Alpha-Amyrin induces proliferation of human keratinocytes. 4. Alpha-Amyrin can as a hepatomodulatory potent to feasibility for a promising liver curative drug. | |
| BCN3496 | Cochinchinenin A |
| The combination of Cochinchinenin A, cochinchinenin B, and loureirin B is the material basis for the analgesic effect of Dragon’s Blood. | |
| BCN3568 | Flavokawain B |
| Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-κB and MAPK signaling pathways. Flavokawain B has potent anti-inflammatory, and anti-cancer activities, it can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. Flavokawain B acts through ROS generation and GADD153 up-regulation to regulate the expression of Bcl-2 family members, thereby inducing mitochondrial dysfunction and apoptosis in HCT116 cells. | |
| BCN3646 | Dehydroeburicoic acid |
| 1. Dehydroeburicoic acid treatment resulted in a marked decrease of tumor weight and size without any significant decrease in mice body weights. 2. Dehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in human glioblastomas. 3. Dehydroeburicoic acid and Eburicoic acid have antioxidant and anti-inflammatory activities by the decrease of inflammatory cytokines and an increase of antioxidant enzyme activity, can protect the liver from CCl4-induced hepatic damage. | |
| BCN3697 | Benzyl 2,6-dimethoxybenzoate |
| 1. Benzyl 2,6-dimethoxybenzoate shows significant analgesic effects. 2. Benzyl 2,6-dimethoxybenzoate induces a concentration-dependent inhibition of the spontaneous contractions of the guinea-pig ileum with IC50 values ranging from 1.49 to 4.96 microM. 3. Benzyl 2,6-dimethoxybenzoate shows antimicrobial activity against several bacteria (S. aureus, E. coli, P. aeruginosa, and B. subtilis) and fungi (C. albicans and T. mentagrophytes). | |
