Products with
Analgesia bioactivity
Cat.No.
|
Product Name
|
BCN5217 |
Corydalmine
|
1. Corydalmine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains.
2. 1-Corydalmine significantly inhibits spore germination of all the fungi at 100 to 1500 ppm.
3. l-Corydalmine exhibits potent analgesic activity in preclinical models, it is under development as an oral analgesic agent. |
BCN5226 |
Sideroxylin
|
1. Sideroxylin can synergistically enhance the antimicrobial activity of the alkaloid berberine (also a constituent of H. canadensis) against Staphylococcus aureus by inhibition of the NorA multidrug resistance pump. |
BCN5228 |
gamma-Mangostin
|
gamma-Mangostin is a dual agonist that activates both PPARδ and PPARα, is also a novel competitive antagonist for the 5-HT2A receptors in vascular smooth muscles and platelets.gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic activity in HepG2 cells, and exhibits antihypertensive, anti-inflammatory, analgesic effects. gamma-Mangostin could as a preventive agent of the metabolic syndrome, and could serve as a micronutrient for colon cancer prevention. |
BCN5259 |
Hypophyllanthin
|
1. Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
2. Hypophyllanthin can modulate the vascular tension via the endothelium-independent mechanisms.
3. Hypophyllanthin can directly inhibit P-gp activity and does not interfere with MRP2 activity, it may reversibly inhibit P-gp function.
4. Hypophyllanthin offers a promising means for treatment of chronic muscle pain.
5. Hypophyllanthin has estrogenic properties against carbofuran induced toxicity in female rats. |
BCN5318 |
3'-O-Methylorobol
|
1. 3'-O-Methylorobol can increase osteoblast differentiation.
2. 3'-O-Methylorobol exerts potential analgesic properties.
3. 3'-O-Methylorobol exhibites moderate antioxidant activity in the 2,2-diphenyl-1-picrylhydrazyl free radical scavenging assay. |