Products with Analgesia bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4187 | Shanzhiside methylester |
| Shanzhiside methylester reduces neuropathic pain by activating spinal GLP-1 receptors and subsequently stimulating microglial β-endorphin expression via the p38 MAPK signaling. | |
| BCN4280 | Specioside |
| 1. Specioside has analgesic activity. 2. Specioside has anti-dyspeptic and astringent activities. 3. Specioside has liver stimulating and wound healing activities. 4. Specioside exhibits potent antioxidant activity. 5. Specioside ameliorates oxidative stress and promotes longevity in Caenorhabditis elegans. | |
| BCN4600 | Kaurenoic acid |
| Kaurenoic acid has anti-inflammatory, analgesic, antimicrobial, cytotoxic and embryotoxic effects; it exerts a uterine relaxant effect acting principally through calcium blockade and in part, by the opening of ATP-sensitive potassium channels. Kaurenoic acid involves the inhibition of cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway. | |
| BCN4607 | Akuammigine |
| 1. Akuammidine shows a preference for mu-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 microM at mu-, delta- and kappa-opioid binding sites, respectively; the agonist actions of akuammidine in the mouse-isolated vas deferens were antagonised by naloxone and the mu-opioid receptor selective antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) confirming an action at mu-opioid receptors. 2. Akuammigine competitively antagonizes the effect of noradrenaline on postsynaptic alpha-adrenoceptors, yielding pA2 values of 4.68. 3. Akuammigine has in vitro antimalarial activity. | |
| BCN4617 | Nimbin |
| 1. Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. 2. Nimbin requires to elicit a 50% inhibition of this steroid hydroxylase activity in the three insect species examined ranged from approximately 2 x 10(-5) to 1 x 10(-3). 3. Nimbin shows anti-feedant activity and toxicity against larvae of three species of Lepidoptera, Spodoptera littoralis (Boisd), Spodoptera frugiperda (FE Smith) and Helicoverpa armigera (Hübner) and nymphs of the locusts Schistocerca gregaria (Forskål) and Locusta migratoria (L). | |
