Products with Anti-Atherosclerotic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6296 | 2-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid |
| Danshensu has anxiolytic-like, cardioprotective, neuroprotective, and antioxidant activities. It can enhance HO-1 expression to suppress 6-OHDA-induced oxidative damage via PI3K/Akt/Nrf2 signaling pathways and can reduce 6-OHDA-induced dopaminergic neuronal loss in zebrafish. Chronic treatment with danshensu can prevent/attenuate the formation of atherosclerosis. | |
| BCN6312 | Naringin |
| Naringin exhibits antioxidant, anti-atherogenic, antiulcer, anti-hypocholesterolemic, anti-lipoperoxidative, and anti-hyperglycemia effects. Naringin reduces Ara-C-induced oxidative stress through both an inhibition of the generation of ROS production and an increase in antioxidant enzyme activities, it blocks apoptosis caused by Ara-C-induced oxidative stress, resulting in the inhibition of the cytotoxicity of Ara-C. Naringin attenuates epidermal growth factor (EGF)-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IκB-NF-κB signaling pathways. | |
| BCN6352 | Senkyunolide H |
| 1. Senkyunolide H, senkyunolide I and ferulic acid can reduce the metamorphose damage of the RBC caused by ConA, the aggregation of the RBC also could be alleviated by them. 2. Senkyunolide H in cnidium rhizome may be a prototype for an anti-atherosclerotic drug. | |
| BCN6709 | Maltotetraose |
| 1. Maltotetraose and stachyose are potent inhibitors of TNF-α-induced intercellular adhesion molecule-1 (ICAM-1) expression, maltotetraose may be beneficial in the suppression of early atherosclerosis development and could be developed as a dietary supplement for cardiovascular health. | |
| BCN6770 | Brandioside |
| 1. Brandioside exhibits significant inhibition of advanced glycation end product formation with the IC50 value of 4.6-25.7 uM. 2. Brandioside significantly attenuates glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 microM. 3. Brandioside shows inhibition of smooth muscle cell proliferation, indicates that it may have preventative effects on arteriosclerosis. 4. Brandioside shows strong antioxidant effect. | |
