Products with Anti-Parkinson bioactivity

Cat.No. Product Name
BCN2295 Desmethoxy yangonin
Desmethoxyyangonin is a reversible inhibitor of MAO-B, it may have important therapeutic value for treatment of neurodegenerative disorders and Parkinson's Disease. Desmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways.
BCN2319 Ginkgetin
Ginkgetin is a good STAT3 inhibitor , which has anti-inflammatory, neuroprotective, anti-influenza virus and anti-fungal activities. Ginkgetin induces apoptosis in PC-3 cells via activation of caspase 3 and inhibition of survival genes as a potent chemotherapeutic agent for prostate cancer treatment.
BCN2328 Anemoside A3
Anemoside A3 is an attractive candidate for further development as a cognitive enhancer capable of alleviating memory dysfunctions associated with aging and neurodegenerative diseases. Anemoside A3 also produces relaxation in rat renal arteries through multiple mechanisms.
BCN3143 1,2-Didehydrotanshinone IIA
1. 1,2-Didehydrotanshinone IIA shows inhibitory effects against acetyl- (AChE) and butyrylcholinesterase (BChE). 2. 1,2-Didehydrotanshinone IIA possesses metal-chelation capacity.
BCN3707 Delta3,2-Hydroxylbakuchiol
1. Delta3,2-Hydroxylbakuchiol acts by protecting dopaminergic neurons from MPP(+) injury and preventing against MPTP-induced behavioral and histological lesions in the Parkinson's disease (PD) model, possibly by inhibiting monoamine transporters. 2. Delta3,2-Hydroxylbakuchiol, a monoamine transporter inhibitor involved in regulating dopaminergic and noradrenergic neurotransmission and may have represented potential pharmacotherapies for disorders such as Parkinson's disease, depression, and cocaine addiction.

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